Title:
THE MEDICAMENT FOR TREATING HYPERPHOSPHEREMIA AND PREPARATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2007/109929
Kind Code:
A1
Abstract:
The medicament for treating hyperphospheremia and preparative method thereof are provided. The medicament comprises lanthanum polystyrene sulfonate as the active ingredient and pharmaceutic adjuvant. The preparative method in the invention comprises: acidizing polystyrene sulfonate by hydrochloric acid, and soaking or eluting the obtained polystyrene sulfonic acid by water-solubility lanthanum salt solution, then washing to neutral PH by water, washing out non-exchanged redundant lanthanum ions, drying the obtained lanthanum polystyrene sulfonate and crushing to powders, the lanthanum in the lanthanum polystyrene sulfonate is 14-22 wt, and the said lanthanum polystyrene sulfonate and usual dose pharmaceutic adjuvant are prepared to the medicament suitable for gastrointestinal tract according to common preparative method. The medicament in the invention can be administered by gastrointestinal tract route, and form insolubility conjugate with phosphate in the digestive tract, then eliminate from digestive tract,, thus achieve the purpose of treating hyperphospheremia.
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Inventors:
LI, Shibiao (N?81 East Qian Fo Shan Road J, inan, Shandong 3, 250013, CN)
李诗标 (中国山东省济南市千佛山东路81号, Shandong 3, 250013, CN)
QIAO, Min (No.81 East Qian Fo Shan Road, Jinan, Shandong 3, 250013, CN)
李诗标 (中国山东省济南市千佛山东路81号, Shandong 3, 250013, CN)
QIAO, Min (No.81 East Qian Fo Shan Road, Jinan, Shandong 3, 250013, CN)
Application Number:
CN2006/001463
Publication Date:
October 04, 2007
Filing Date:
June 26, 2006
Export Citation:
Assignee:
LI, Shibiao (N?81 East Qian Fo Shan Road J, inan, Shandong 3, 250013, CN)
李诗标 (中国山东省济南市千佛山东路81号, Shandong 3, 250013, CN)
QIAO, Min (No.81 East Qian Fo Shan Road, Jinan, Shandong 3, 250013, CN)
李诗标 (中国山东省济南市千佛山东路81号, Shandong 3, 250013, CN)
QIAO, Min (No.81 East Qian Fo Shan Road, Jinan, Shandong 3, 250013, CN)
International Classes:
A61K33/24; A61P3/12
Attorney, Agent or Firm:
SHAN DONG JI NAN QI LU SCIENCE PATENT OFFICE LTD (N?157, Jing Shi East Rd. Lixia J,inan S, handong 4, 250014, CN)
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