Title:
MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER
Document Type and Number:
WIPO Patent Application WO/2023/008461
Kind Code:
A1
Abstract:
The present invention relates to a medicament for the treatment and/or prevention of cancer, the medicament being characterized by comprising an antibody having an immunological reactivity with CAPRIN-1 protein or a fragment of the antibody and a drug capable of inhibiting the N-glycoside-linked sugar chain synthesis of a glycoprotein which are combined with each other in a blended or separated form.
Inventors:
KUME MASAHIKO (JP)
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
Application Number:
PCT/JP2022/028877
Publication Date:
February 02, 2023
Filing Date:
July 27, 2022
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K39/395; A61K31/7072; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07K16/28; C07K16/46; C12N9/99; C12N15/13
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CANCER CELL, vol. 36, no. 1, 2019, pages 6 - 16
J.CLIN.CANCER RES, vol. 37, no. 1, 2018, pages 272
BIOMED.PHARMACOTHER, vol. 74, 2015, pages 49 - 56
CANCER RES, vol. 80, no. 11, 2020, pages 2298 - 2310
NAT.COMMUN, vol. 7, 2016, pages 12632
KARLINALTSCHUL, PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
SATO K. ET AL., CANCER RESEARCH, vol. 53, 1993, pages 851 - 856
KOHLER, G.MILSTEIN, C, METHODS ENZYMOL., vol. 73, 1981, pages 3 - 46
MITACHI KATSUHIKO, KANSAL RITA G., HEVENER KIRK E., GILLMAN CODY D., HUSSAIN SYED M., YUN HYUN GI, MIRANDA-CARBONI GUSTAVO A., GLA: "DPAGT1 Inhibitors of Capuramycin Analogues and Their Antimigratory Activities of Solid Tumors", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 63, no. 19, 8 October 2020 (2020-10-08), US , pages 10855 - 10878, XP055897324, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.0c00545
HOU HELEI, SUN HEFEN, LU PING, GE CHAO, ZHANG LIXING, LI HONG, ZHAO FANGYU, TIAN HUA, ZHANG LIN, CHEN TAOYANG, YAO MING, LI JINJUN: "Tunicamycin Potentiates Cisplatin Anticancer Efficacy through the DPAGT1/Akt/ABCG2 Pathway in Mouse Xenograft Models of Human Hepatocellular Carcinoma", MOLECULAR CANCER THERAPEUTICS, AMERICAN ASSOCIATION FOR CANCER RESEARCH, US, vol. 12, no. 12, 1 December 2013 (2013-12-01), US , pages 2874 - 2884, XP093028392, ISSN: 1535-7163, DOI: 10.1158/1535-7163.MCT-13-0201
CANCER CELL, vol. 36, no. 1, 2019, pages 6 - 16
J.CLIN.CANCER RES, vol. 37, no. 1, 2018, pages 272
BIOMED.PHARMACOTHER, vol. 74, 2015, pages 49 - 56
CANCER RES, vol. 80, no. 11, 2020, pages 2298 - 2310
NAT.COMMUN, vol. 7, 2016, pages 12632
KARLINALTSCHUL, PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
SATO K. ET AL., CANCER RESEARCH, vol. 53, 1993, pages 851 - 856
KOHLER, G.MILSTEIN, C, METHODS ENZYMOL., vol. 73, 1981, pages 3 - 46
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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