Title:
MEDICATION FOR INFLUENZA
Document Type and Number:
WIPO Patent Application WO/2019/069561
Kind Code:
A1
Abstract:
A medication for preventing or treating influenza, said medication including an inactivated influenza virus or a recombinant vaccinia virus that includes, within the genome of the vaccinia virus DIs strain, an expression promoter and all or a portion of DNA coding for an influenza virus-derived protein.
Inventors:
YASUI FUMIHIKO (JP)
KOHARA MICHINORI (JP)
KOHARA MICHINORI (JP)
Application Number:
PCT/JP2018/030141
Publication Date:
April 11, 2019
Filing Date:
August 10, 2018
Export Citation:
Assignee:
TOKYO METROPOLITAN INST MEDICAL SCIENCE (JP)
International Classes:
A61K35/17; A61K35/76; A61K39/145; A61K39/275; A61K39/395; A61K45/00; A61P31/16
Domestic Patent References:
| WO2006038742A1 | 2006-04-13 |
Foreign References:
| JP2013048597A | 2013-03-14 | |||
| JP2017510297A | 2017-04-13 | |||
| JP2017122087A | 2017-07-13 | |||
| JP2014511704A | 2014-05-19 | |||
| JP2015509974A | 2015-04-02 | |||
| JP2016178945A | 2016-10-13 | |||
| JP2828340B2 | 1998-11-25 | |||
| JP5884100B2 | 2016-03-15 | |||
| JPH06237773A | 1994-08-30 |
Other References:
UNAKATA KEISUKE ET AL.: "1-2-06 Investigation of protective effect of vaccinia virus Dis strain as a maternal influenza HA recombinant vaccine in cynomolgus monkeys", PROGRAM AND PROCEEDINGS OF THE MEETING OF THE JAPANESE SOCIETY FOR VACCINOLOGY; OCTOBER 22-23, 2016, 2016, pages 91, XP009519361
ETO AKIKO ET AL.: "Examination on aging and booster effect of comprehensive antibody production after smallpox vaccine LC16m8 inoculation : Comparative with first generation vaccine", PROGRAM AND PROCEEDING OF THE MEETING OF THE JAPANESE SOCIETY OF VACCINOLOGY, 21 December 2017 (2017-12-21), pages 102, XP009519293
MUARAKAMI S. ET AL.: "Cross-clade protective immunity ofH5Nl influenza vaccines in a mouse model", VACCINE, vol. 26, no. 50, 2008, pages 6398 - 6404, XP025658437, DOI: 10.1016/j.vaccine.2008.08.053
TSUKIYAMA K. ET AL.: "Development of heat-stable recombinant rinderpest vaccine", ARCH. VIROL., vol. 107, 1989, pages 225 - 235, XP000351661, DOI: 10.1007/BF01317919
KITABATAKE M. ET AL.: "SARS-CoV spike protein-expressing recombinant vaccinia virus efficiently induces neutralizing antibodies in rabbits pre-immunized with vaccinia virus", VACCINE, vol. 25, 2007, pages 630 - 637, XP005798920, DOI: 10.1016/j.vaccine.2006.08.039
YASUI F. ET AL.: "Sensitization with vaccinia virus encoding H5N1 hemagglutinin restore immune potential against H5N1 influenza virus", SCI. REP., vol. 6, 2016, pages 37915
TAGAYA I ET AL.: "A new mutant of dermovaccinia virus", NATURE, vol. 192, 1961, pages 1187 - 1188
MORIKAWA S. ET AL.: "An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection", J. VIROL., vol. 79, no. 18, 2005, pages 11873 - 1189
PROC. NATL. ACAD. SCI. U.S.A., vol. 81, 1984, pages 6851 - 6855
NATURE, vol. 321, 1986, pages 522 - 525
J. MOL. BIOL., vol. 196, 1987, pages 901 - 917
QUEEN C ET AL., PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 10029 - 10033
TOMIZUKA, K. ET AL., NATURE GENETICS, vol. 16, 1977, pages 133 - 143
KUROIWA, Y. ET AL., NUC. ACIDS RES., vol. 26, 1998, pages 3447 - 3448
YOSHIDA, H. ET AL.: "Animal Cell Technology: Basic and Applied Aspects", vol. 10, 1999, KLUWER ACADEMIC PUBLISHERS, pages: 69 - 73
TOMIZUKA, K. ET AL., PROC. NATL. ACAD. SCI. USA, vol. 97, 2000, pages 722 - 727
WORMSTONE, 1. M. ET AL., INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 43, no. 7, 2002, pages 2301 - 8
CARMEN, S. ET AL., BRIEFINGS IN FUNCTIONAL GENOMICS AND PROTEOMICS, vol. 1, no. 2, 2002, pages 189 - 203
SIRIWARDENA, D. ET AL., OPTHALMOLOGY, vol. 109, no. 3, 2002, pages 427 - 431
"Molecular Cloning, A Laboratory Manual", 2012, COLD SPRING HARBOR LABORATORY PRESS
"Current Protocols in Molecular Biology", 1987, JOHN WILEY & SONS
VIROLOGY, vol. 351, pages 368 - 380
ARCH. VIROL., vol. 138, 1994, pages 315 - 330
See also references of EP 3692997A4
ETO AKIKO ET AL.: "Examination on aging and booster effect of comprehensive antibody production after smallpox vaccine LC16m8 inoculation : Comparative with first generation vaccine", PROGRAM AND PROCEEDING OF THE MEETING OF THE JAPANESE SOCIETY OF VACCINOLOGY, 21 December 2017 (2017-12-21), pages 102, XP009519293
MUARAKAMI S. ET AL.: "Cross-clade protective immunity ofH5Nl influenza vaccines in a mouse model", VACCINE, vol. 26, no. 50, 2008, pages 6398 - 6404, XP025658437, DOI: 10.1016/j.vaccine.2008.08.053
TSUKIYAMA K. ET AL.: "Development of heat-stable recombinant rinderpest vaccine", ARCH. VIROL., vol. 107, 1989, pages 225 - 235, XP000351661, DOI: 10.1007/BF01317919
KITABATAKE M. ET AL.: "SARS-CoV spike protein-expressing recombinant vaccinia virus efficiently induces neutralizing antibodies in rabbits pre-immunized with vaccinia virus", VACCINE, vol. 25, 2007, pages 630 - 637, XP005798920, DOI: 10.1016/j.vaccine.2006.08.039
YASUI F. ET AL.: "Sensitization with vaccinia virus encoding H5N1 hemagglutinin restore immune potential against H5N1 influenza virus", SCI. REP., vol. 6, 2016, pages 37915
TAGAYA I ET AL.: "A new mutant of dermovaccinia virus", NATURE, vol. 192, 1961, pages 1187 - 1188
MORIKAWA S. ET AL.: "An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection", J. VIROL., vol. 79, no. 18, 2005, pages 11873 - 1189
PROC. NATL. ACAD. SCI. U.S.A., vol. 81, 1984, pages 6851 - 6855
NATURE, vol. 321, 1986, pages 522 - 525
J. MOL. BIOL., vol. 196, 1987, pages 901 - 917
QUEEN C ET AL., PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 10029 - 10033
TOMIZUKA, K. ET AL., NATURE GENETICS, vol. 16, 1977, pages 133 - 143
KUROIWA, Y. ET AL., NUC. ACIDS RES., vol. 26, 1998, pages 3447 - 3448
YOSHIDA, H. ET AL.: "Animal Cell Technology: Basic and Applied Aspects", vol. 10, 1999, KLUWER ACADEMIC PUBLISHERS, pages: 69 - 73
TOMIZUKA, K. ET AL., PROC. NATL. ACAD. SCI. USA, vol. 97, 2000, pages 722 - 727
WORMSTONE, 1. M. ET AL., INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 43, no. 7, 2002, pages 2301 - 8
CARMEN, S. ET AL., BRIEFINGS IN FUNCTIONAL GENOMICS AND PROTEOMICS, vol. 1, no. 2, 2002, pages 189 - 203
SIRIWARDENA, D. ET AL., OPTHALMOLOGY, vol. 109, no. 3, 2002, pages 427 - 431
"Molecular Cloning, A Laboratory Manual", 2012, COLD SPRING HARBOR LABORATORY PRESS
"Current Protocols in Molecular Biology", 1987, JOHN WILEY & SONS
VIROLOGY, vol. 351, pages 368 - 380
ARCH. VIROL., vol. 138, 1994, pages 315 - 330
See also references of EP 3692997A4
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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