Title:
MEDICINAL AGENT FOR PREVENTION AND/OR TREATMENT OF HEPATITIS C
Document Type and Number:
WIPO Patent Application WO/2011/135743
Kind Code:
A1
Abstract:
A medicinal agent for preventing and/or treating hepatitis C, which comprises a combination of an HMG-CoA reductase inhibitor, a salt thereof or a solvate of the inhibitor or the salt and a non-cyclic retinoid, a salt thereof or a solvate of the retinoid or the salt.
Inventors:
MORIGUCHI HISASHI (JP)
SATO CHIFUMI (JP)
OZAWA TAKATOSHI (JP)
SATO CHIFUMI (JP)
OZAWA TAKATOSHI (JP)
Application Number:
PCT/JP2010/069787
Publication Date:
November 03, 2011
Filing Date:
November 08, 2010
Export Citation:
Assignee:
KOWA CO (JP)
NAT UNIV CORP TOKYO MED & DENT (JP)
MORIGUCHI HISASHI (JP)
SATO CHIFUMI (JP)
OZAWA TAKATOSHI (JP)
NAT UNIV CORP TOKYO MED & DENT (JP)
MORIGUCHI HISASHI (JP)
SATO CHIFUMI (JP)
OZAWA TAKATOSHI (JP)
International Classes:
A61K45/06; A61K31/202; A61K31/473; A61P31/14; A61P43/00
Domestic Patent References:
| WO2003097034A1 | 2003-11-27 |
Foreign References:
| JPH10167960A | 1998-06-23 |
Other References:
MORIGUCHI, H. ET AL.: "An identification of the novel combination therapy for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells", HEPATOLOGY, vol. 51, no. 1, January 2010 (2010-01-01), pages 351 - 352
MORIGUCHI, H. ET AL.: "New translational research on novel drugs for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells", HEPATOLOGY, vol. 51, no. 1, January 2010 (2010-01-01), pages 344 - 345
IKEDA, M. ET AL.: "Life style-related diseases of the digestive system: cell culture system for the screening of anti-hepatitis C virus (HCV) reagents: suppression of HCV replication by statins and synergistic action with interferon", J PHARMACOL SCI, vol. 105, no. 2, 2007, pages 145 - 150
DELANG, L. ET AL.: "Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development", HEPATOLOGY, vol. 50, no. 1, 2009, pages 6 - 16
MUTO, Y. ET AL.: "PREVENTION OF LIVER CARCINOGENESIS WITH ACYCLIC RETINOID", RECENT ADVANCES IN GASTROENTEROLOGICAL CARCINOGENESIS, vol. 1, 1996, pages 169 - 172
MORIGUCHI, H. ET AL.: "New translational research on novel drugs for hepatitis C virus 1b infection by using a replicon system and human induced pluripotent stem cells", HEPATOLOGY, vol. 51, no. 1, January 2010 (2010-01-01), pages 344 - 345
IKEDA, M. ET AL.: "Life style-related diseases of the digestive system: cell culture system for the screening of anti-hepatitis C virus (HCV) reagents: suppression of HCV replication by statins and synergistic action with interferon", J PHARMACOL SCI, vol. 105, no. 2, 2007, pages 145 - 150
DELANG, L. ET AL.: "Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development", HEPATOLOGY, vol. 50, no. 1, 2009, pages 6 - 16
MUTO, Y. ET AL.: "PREVENTION OF LIVER CARCINOGENESIS WITH ACYCLIC RETINOID", RECENT ADVANCES IN GASTROENTEROLOGICAL CARCINOGENESIS, vol. 1, 1996, pages 169 - 172
Attorney, Agent or Firm:
SIKs & Co. (JP)
Patent business corporation patent firm Sykes (JP)
Patent business corporation patent firm Sykes (JP)
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