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Title:
MEDICINAL COMPOSITION FOR TREATING BULIMIA AND DEPRESSION ACCOMPANYING BULIMIA
Document Type and Number:
WIPO Patent Application WO/2007/034910
Kind Code:
A1
Abstract:
It is intended to provide a medicinal composition which comprises a choline esterase inhibitor combined with at least one member selected from the group consisting of sibutramine, a pharmacologically acceptable salt thereof, an active metabolite thereof, a prodrug thereof and a solvate thereof. This medicinal composition is useful in treating bulimia and depression accompanying bulimia.

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Inventors:
SAKAI KAZUO (JP)
Application Number:
PCT/JP2006/318838
Publication Date:
March 29, 2007
Filing Date:
September 22, 2006
Export Citation:
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Assignee:
EISAI R&D MAN CO LTD (JP)
SAKAI KAZUO (JP)
International Classes:
A61K31/137; A61K31/27; A61K31/407; A61K31/445; A61K31/473; A61K31/553; A61K31/662; A61K45/00; A61P3/04; A61P25/18; A61P25/24; A61P43/00
Domestic Patent References:
WO2005051297A22005-06-09
Foreign References:
JP2003519087A2003-06-17
US6521266B12003-02-18
JP2003504303A2003-02-04
JP2004231588A2004-08-19
JPH02503682A1990-11-01
Other References:
MITCHELL J.E. ET AL.: "Effects of sibutramine on binge eating, hunger, and fullness in a laboratory human feeding paradigm", OBESITY RESEARCH, vol. 11, no. 5, 2003, pages 599 - 602, XP003003878
ADAMS P.M.: "Effects of anticholinergic and cholinesterase blocking drugs on appetitive behavior under different deprivation conditions", LIFE SCIENCES, vol. 21, no. 1, 1977, pages 129 - 135, XP003003879
See also references of EP 1938811A4
Attorney, Agent or Firm:
KATO, Asamichi et al. (daVinci BOSEI 7th Floor,, 20-12, Shin-Yokohama 3-chome,, Kohoku-ku, Yokohama-sh, Kanagawa 33, JP)
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