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Title:
MEDICINAL COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME
Document Type and Number:
WIPO Patent Application WO/2002/043766
Kind Code:
A1
Abstract:
Compositions wherein the release of a nonpeptidic GnRH agonist and antagonist having a particularly low solubility is accelerated. Namely, compositions containing a hardly water-soluble nonpeptidic gonadotropin-releasing hormone agonist or antagonist and an aromatic hydroxycarboxylic acid or its salt.

Inventors:
YAMAGATA YUTAKA (JP)
HATA YOSHIO (JP)
Application Number:
PCT/JP2001/010417
Publication Date:
June 06, 2002
Filing Date:
November 29, 2001
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
YAMAGATA YUTAKA (JP)
HATA YOSHIO (JP)
International Classes:
A61K9/00; A61K9/16; A61P5/04; A61P15/00; A61P15/08; A61P17/10; A61P17/14; A61P25/28; A61P35/00; C07D495/04; (IPC1-7): A61K47/12; A61K9/127; A61K9/51; A61K31/4436; A61K31/519; A61K45/00; A61K47/36; A61P5/04; A61P15/00; A61P15/08; A61P17/10; A61P17/14; A61P25/28; A61P35/00; C07D495/04
Domestic Patent References:
WO2000056739A12000-09-28
WO1995028405A11995-10-26
WO1998032423A11998-07-30
WO1994025460A11994-11-10
WO1999036099A11999-07-22
Foreign References:
JPH11199521A1999-07-27
EP0566135A11993-10-20
JPS6393714A1988-04-25
EP0569096A11993-11-10
JPS5734822B21982-07-26
EP0503583A11992-09-16
JPH07196510A1995-08-01
JPH1045616A1998-02-17
Attorney, Agent or Firm:
Aoyama, Tamotsu (Shiromi 1-chome Chuo-ku, Osaka-shi Osaka, JP)
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