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Title:
MEDICINAL COMPOSITIONS FOR TOPICAL ADMINISTRATION CONTAINING VITAMIN D AND VITAMIN K
Document Type and Number:
WIPO Patent Application WO/1998/053806
Kind Code:
A1
Abstract:
Ophthalmic compositions for preventing corneal clouding and corneal refraction insufficiency, ultraviolet protective agents for protecting the ocular tissue or skin from harmful UV light, or antiallergic agents for topical administration, each containing vitamin Ds or vitamin Ks as the active ingredient.

Inventors:
ITOH SEIJI
ISHII YASUO
MUKAI KATSUHIKO
KITA KIYOSHI
Application Number:
PCT/JP1997/001761
Publication Date:
December 03, 1998
Filing Date:
May 26, 1997
Export Citation:
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Assignee:
NEW VISION CO LTD (JP)
International Classes:
A61K9/00; A61K31/122; A61K31/59; A61K31/592; A61K31/593; A61K45/06; A61P27/02; A61P37/08; H01R39/38; H02K5/14; H02K13/00; (IPC1-7): A61K31/12; A61K31/59
Domestic Patent References:
WO1996029079A11996-09-26
WO1984002845A11984-08-02
Foreign References:
JPH05503922A1993-06-24
JPH05508655A1993-12-02
JPS63145233A1988-06-17
JPH0324016A1991-02-01
JPH057619A1993-01-19
JPS62263110A1987-11-16
US4610978A1986-09-09
JPS61267458A1986-11-27
JPS624262A1987-01-10
EP0512814A11992-11-11
JPH01124395A1989-05-17
Other References:
BIDMON HANS-JURGEN et al., "1,25-Dihydroxyvitamin D3 Binding Sites in the Eye and Associated Tissues of the Green Lizard Anolis Carolinensis", HISTOCHEM. J., Vol. 27, No. 7, (1995), p. 516-523.
ABDEL-MALEK ZALFA A. et al., "Hormonal Effects of Vitamin D3 on Epidermal Melanocytes", J. CELL. PHYSIOL., Vol. 136, No. 2, (1988), p. 273-280.
LIU XIN HUA et al., "The Inhibition of Vitamin K3 on Rabbit Fibroblast Proliferation In Vitro", OPHTHALMOLOGICA, Vol. 210, No. 3, (1996), p. 180-182.
REEVE JEFF et al., "Are Natural Lipids UV-Screening Agents?", APPL. MICROBIOL. BIOTECHNOL., Vol. 33, No. 2, (1990), p. 161-166.
See also references of EP 0998925A4
Attorney, Agent or Firm:
Nakamura, Minoru (Shin-Tokyo Building 3-1, Marunouchi 3-chom, Chiyoda-ku Tokyo 100, JP)
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