Title:
MEDICINE FOR PREVENTING ISCHEMIC DISEASES
Document Type and Number:
WIPO Patent Application WO/2015/114900
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a prophylactic agent for retinal disorders including ischemic retinal disorders. The present invention specifically relates to a prophylactic agent for retinal disorders, which contains, as an active ingredient, a carotenoid mixture containing astaxanthin as the main component.
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Inventors:
HARA HIDEAKI (JP)
ISHIBASHI TAKASHI (JP)
ISHIBASHI TAKASHI (JP)
Application Number:
PCT/JP2014/078677
Publication Date:
August 06, 2015
Filing Date:
October 22, 2014
Export Citation:
Assignee:
JX NIPPON OIL & ENERGY CORP (JP)
International Classes:
A23L1/30; A61K31/122; A23L2/52; A61K35/74; A61P27/02; A61P27/06
Domestic Patent References:
| WO1996013255A1 | 1996-05-09 |
Foreign References:
| JP2012025712A | 2012-02-09 | |||
| JPH10155459A | 1998-06-16 | |||
| JP2006008720A | 2006-01-12 | |||
| JP2014016118A | 2014-01-30 | |||
| JP2009050237A | 2009-03-12 |
Other References:
OTSUKA T. ET AL.: "The protective effects of a dietary carotenoid, astaxanthin, against light- induced retinal damage", J.PHARMACOL.SCI., vol. 123, 2013, pages 209 - 218, XP055217499
YASUNORI NAGAKI ET AL.: "Astaxanthin no Momaku Kekkan Ketsuryuryo ni Oyobosu Eikyo", JOURNAL OF CLINICAL THERAPEUTICS & MEDICINES, vol. 21, no. 5, 2005, pages 537 - 542, XP008183928
YOSHIMI NAKASHIMA ET AL.: "Astaxanthin Oyobi Zeaxanthin no Sanka Stress ni yoru Momaku Shogai ni Taisuru Koka", ABSTRACTS OF ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN, vol. 127 TH, no. 4, 2007, pages 114, 30P1 - PM133, XP008183897
OGISHIMA H. ET AL.: "Ligation of the Pterygopalatine and External Carotid Arteries Induces Ischemic Damage in the Murine Retina", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 52, no. 13, 2011, pages 9710 - 9720
MURINE RETINA, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 52, no. 13, 2011, pages 9710 - 9720
NAKAJIMA Y. ET AL.: "Zeaxanthin, a Retinal Carotenoid, Protects Retinal Cells against Oxidative Stress", CURRENT EYE RESEARCH, vol. 34, 2009, pages 311 - 318
OTSUKA T. ET AL.: "The Protective Effects of a Dietary Carotenoid, Astaxanthin, Against Light-Induced Retinal Damage", JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. 123, no. 3, 2013, pages 209 - 218
See also references of EP 3100724A4
YASUNORI NAGAKI ET AL.: "Astaxanthin no Momaku Kekkan Ketsuryuryo ni Oyobosu Eikyo", JOURNAL OF CLINICAL THERAPEUTICS & MEDICINES, vol. 21, no. 5, 2005, pages 537 - 542, XP008183928
YOSHIMI NAKASHIMA ET AL.: "Astaxanthin Oyobi Zeaxanthin no Sanka Stress ni yoru Momaku Shogai ni Taisuru Koka", ABSTRACTS OF ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN, vol. 127 TH, no. 4, 2007, pages 114, 30P1 - PM133, XP008183897
OGISHIMA H. ET AL.: "Ligation of the Pterygopalatine and External Carotid Arteries Induces Ischemic Damage in the Murine Retina", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 52, no. 13, 2011, pages 9710 - 9720
MURINE RETINA, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, vol. 52, no. 13, 2011, pages 9710 - 9720
NAKAJIMA Y. ET AL.: "Zeaxanthin, a Retinal Carotenoid, Protects Retinal Cells against Oxidative Stress", CURRENT EYE RESEARCH, vol. 34, 2009, pages 311 - 318
OTSUKA T. ET AL.: "The Protective Effects of a Dietary Carotenoid, Astaxanthin, Against Light-Induced Retinal Damage", JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. 123, no. 3, 2013, pages 209 - 218
See also references of EP 3100724A4
Attorney, Agent or Firm:
HIRAKI, Yusuke et al. (JP)
Yusuke Hiraki (JP)
Yusuke Hiraki (JP)
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