Title:
MEDICINE FOR SUPPRESSING MALIGNANT TUMOR METASTASIS
Document Type and Number:
WIPO Patent Application WO/2015/152393
Kind Code:
A1
Abstract:
The present invention provides a novel medicine for suppressing or preventing metastasis of malignant tumors in cancer, etc., and a novel treatment or prevention method for suppressing or preventing metastasis of malignant tumors. This medicine contains a non-peptide angiotensin type-2 receptor agonist as an active ingredient. The non-peptide angiotensin type-2 receptor agonist in this medicine may be a malonic acid sulfonamide compound, for example. Furthermore, this medicine may be a medicine to be used along with an anticancer drug and/or an antitumor drug.
Inventors:
KANGAWA KENJI (JP)
HOSODA HIROSHI (JP)
NOJIRI TAKASHI (JP)
HOSODA HIROSHI (JP)
NOJIRI TAKASHI (JP)
Application Number:
PCT/JP2015/060582
Publication Date:
October 08, 2015
Filing Date:
April 03, 2015
Export Citation:
Assignee:
NAT CEREBRAL & CARDIOVASCULAR CT (JP)
MITSUBISHI TANABE PHARMA CORP (JP)
MITSUBISHI TANABE PHARMA CORP (JP)
International Classes:
A61K45/00; A61K31/18; A61P35/04; A61P43/00
Domestic Patent References:
| WO2014054798A1 | 2014-04-10 | |||
| WO2008156142A1 | 2008-12-24 |
Foreign References:
| JP2004533457A | 2004-11-04 |
Other References:
ZHOU, L. ET AL.: "Role of Two Types of Angiotensin II Receptors in Colorectal Carcinoma Progression", PATHOBIOLOGY, vol. 81, August 2014 (2014-08-01), pages 169 - 175
AGER, E. ET AL.: "Targeting the angiotensin II type 2 receptor( AT 2R) in colorectal liver metastases", CANCER CELL INTERNATIONAL, vol. 10, no. 19, 2010, pages 1 - 12, XP021077242
See also references of EP 3127554A4
AGER, E. ET AL.: "Targeting the angiotensin II type 2 receptor( AT 2R) in colorectal liver metastases", CANCER CELL INTERNATIONAL, vol. 10, no. 19, 2010, pages 1 - 12, XP021077242
See also references of EP 3127554A4
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Tatsu Iwatani (JP)
Tatsu Iwatani (JP)
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