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Title:
MEDICINE
Document Type and Number:
WIPO Patent Application WO/2018/070069
Kind Code:
A1
Abstract:
The present invention provides a medicine comprising: a Toll-like receptor agonist; and LAG-3 protein, a variant thereof, or a derivative thereof.

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Inventors:
MIYAKAWA TOMOYA (JP)
DOI SHUN (JP)
TAMADA KOJI (JP)
Application Number:
PCT/JP2017/015227
Publication Date:
April 19, 2018
Filing Date:
April 14, 2017
Export Citation:
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Assignee:
CYTLIMIC INC (JP)
International Classes:
A61K38/02; A61K31/7088; A61K39/00; A61K39/39; A61K45/00; A61K45/06; A61P35/00; A61P37/04; A61P43/00; C07K14/705
Domestic Patent References:
WO2015168379A22015-11-05
WO2016056596A12016-04-14
WO2016143816A12016-09-15
WO2016163489A12016-10-13
Other References:
KANO Y ET AL.: "Combined adjuvants of pol(I:C) plus LAG-3-Ig improve antitumor effects of tumor-specific T cells, preventing their exhaustion", CANCER SCI., vol. 107, no. 4, April 2016 (2016-04-01), pages 398 - 406, XP055475305, ISSN: 1347-9032, DOI: doi:10.1111/cas.12861
See also references of EP 3527216A4
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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