Title:
MEDIUM COMPOSITION AND METHOD FOR PRODUCING RED BLOOD CELLS USING SAME
Document Type and Number:
WIPO Patent Application WO/2014/171486
Kind Code:
A1
Abstract:
The invention provides a method for producing red blood cells characterized in that hematopoietic stem cells and/or hematopoietic precursor cells are efficiently differentiated into red blood cells using a medium composition having the effect of uniformly dispersing hematopoietic stem cells and/or hematopoietic precursor cells and maintaining a state of suspension.
Inventors:
NISHINO TAITO (JP)
KANAKI TATSURO (JP)
OTANI AYAKO (JP)
SARUHASHI KOICHIRO (JP)
TOMURA MISAYO (JP)
KANAKI TATSURO (JP)
OTANI AYAKO (JP)
SARUHASHI KOICHIRO (JP)
TOMURA MISAYO (JP)
Application Number:
PCT/JP2014/060829
Publication Date:
October 23, 2014
Filing Date:
April 16, 2014
Export Citation:
Assignee:
NISSAN CHEMICAL IND LTD (JP)
International Classes:
C12N1/00; C12N5/0789
Domestic Patent References:
| WO2006090886A1 | 2006-08-31 | |||
| WO2014017513A1 | 2014-01-30 | |||
| WO2009137629A2 | 2009-11-12 | |||
| WO2010098079A1 | 2010-09-02 | |||
| WO2001034776A1 | 2001-05-17 | |||
| WO2011034073A1 | 2011-03-24 |
Foreign References:
| JP2010525836A | 2010-07-29 | |||
| JP2011024423A | 2011-02-10 |
Other References:
KISHIMOTO S. ET AL.: "Cytokine-immobilized microparticle-coated plates for culturing hematopoetic progenitor cells", JOURNAL OF CONTROLLED RELEASE, vol. 133, no. 3, 2009, pages 185 - 190, XP025893046
AYAKO OTANI ET AL.: "Kobunshi Zairyo o Mochiita Shinki Sanjigen Baiyoho no Kaihatsu", DAI 36 KAI THE MOLECULAR BIOLOGY SOCIETY OF JAPAN NENKAI KOEN YOSHISHU, 20 November 2013 (2013-11-20), pages 2P-0990, XP008181249
See also references of EP 2987852A4
MOUNTFORD ET AL., BRITISH JOURNAL OF HAEMATOLOGY, vol. 149, 2010, pages 22 - 34
DOLZNIG ET AL., CURR. BIOL., vol. 12, 2002, pages 1076 - 1085
GIARRATANA ET AL., BLOOD, vol. 118, 2011, pages 5071 - 5079
MA ET AL., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 105, 2008, pages 13087 - 13092
DIAS ET AL., STEM CELLS AND DEVELOPMENT, vol. 20, 2011, pages 1639 - 1647
FUJIMI ET AL., INTERNATIONAL JOURNAL OF HEMATOLOGY, vol. 87, 2008, pages 339 - 350
HIROYAMA ET AL., PLOS ONE, vol. 3, 2008, pages E1544
NATURE, vol. 456, 2008, pages 344 - 349
BLOOD, vol. 102, 2003, pages 906 - 915
TAKAYAMA ET AL., BLOOD, vol. 111, 2008, pages 5298 - 5306
PLOS ONE, vol. 3, 2008, pages E1544
AYAKO OTANI ET AL.: "Kobunshi Zairyo o Mochiita Shinki Sanjigen Baiyoho no Kaihatsu", DAI 36 KAI THE MOLECULAR BIOLOGY SOCIETY OF JAPAN NENKAI KOEN YOSHISHU, 20 November 2013 (2013-11-20), pages 2P-0990, XP008181249
See also references of EP 2987852A4
MOUNTFORD ET AL., BRITISH JOURNAL OF HAEMATOLOGY, vol. 149, 2010, pages 22 - 34
DOLZNIG ET AL., CURR. BIOL., vol. 12, 2002, pages 1076 - 1085
GIARRATANA ET AL., BLOOD, vol. 118, 2011, pages 5071 - 5079
MA ET AL., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 105, 2008, pages 13087 - 13092
DIAS ET AL., STEM CELLS AND DEVELOPMENT, vol. 20, 2011, pages 1639 - 1647
FUJIMI ET AL., INTERNATIONAL JOURNAL OF HEMATOLOGY, vol. 87, 2008, pages 339 - 350
HIROYAMA ET AL., PLOS ONE, vol. 3, 2008, pages E1544
NATURE, vol. 456, 2008, pages 344 - 349
BLOOD, vol. 102, 2003, pages 906 - 915
TAKAYAMA ET AL., BLOOD, vol. 111, 2008, pages 5298 - 5306
PLOS ONE, vol. 3, 2008, pages E1544
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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