MEK INHIBITORS AND THERAPEUTIC USES THEREOF

Title:

MEK INHIBITORS AND THERAPEUTIC USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/142144

Kind Code:

A1

Abstract:

The present disclosure provides compounds, compositions containing such compounds, and methods of designing, developing, producing and preparing compounds represented by general Formula (I), including pharmaceutically acceptable salts thereof or a synthetic intermediate thereof. The compounds act as MEK inhibitors and are capable of displaying one or more beneficial therapeutic effects, including treating cancer.

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Inventors:

HALL BRETT MATTHEW (US)
DECORTE BART LIEVEN (US)
KING PETER JOHN (US)
LEENDERS RUBEN (US)
WEGERT ANITA (US)
FOLWER KEVIN (US)
KOLITZ SARAH (US)
DOODEMAN ROBIN (US)
POELAKKER JARNO (US)
FOLMER RUTGER HENK ADRIAAN (US)

Application Number:

PCT/US2021/012531

Publication Date:

July 15, 2021

Filing Date:

January 07, 2021

Export Citation:

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Assignee:

IMMUNEERING CORP (US)

International Classes:

C07D401/10

Foreign References:

US20160002212A1	2016-01-07
US20100004233A1	2010-01-07

Other References: