MELITTIN-POLYETHYLENE GLYCOL CONJUGATE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

Title:

MELITTIN-POLYETHYLENE GLYCOL CONJUGATE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

Document Type and Number:

WIPO Patent Application WO/2015/190849

Kind Code:

A1

Abstract:

The present invention provides a melittin-polyethylene glycol conjugate in which polyethylene glycol is coupled to an N-terminal amino group of melittin, a method of manufacturing the same, and a pharmaceutical composition for treatment or prevention of an inflammation comprising the same as an active ingredient. The melittin-polyethylene glycol conjugate according to the present invention is less cytotoxic and has an excellent anti-inflammatory effect compared to melittin.

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Inventors:

CHUNG BONG YOUL (KR)
BAE GUN WON (KR)
HA JAE SEOK (KR)
KIM MYEONG SUK (KR)
KIM JAE JOON (KR)

Application Number:

PCT/KR2015/005892

Publication Date:

December 17, 2015

Filing Date:

June 11, 2015

Export Citation:

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Assignee:

HUMEDIX CO LTD (KR)

International Classes:

C07K17/08; A61K38/16; A61K47/48

Foreign References:

US5428128A	1995-06-27
US20110086100A1	2011-04-14
KR20020012278A	2002-02-15
KR20120125754A	2012-11-19
KR101323769B1	2013-10-29

Attorney, Agent or Firm:

YU, Su Mi (KR)
유수미 (KR)

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