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Title:
MEMS-BASED SINGLE PARTICLE SEPARATION SYSTEM
Document Type and Number:
WIPO Patent Application WO/2015/173710
Kind Code:
A3
Abstract:
A particle separation system uses a MEMS-based, microfabricated particle manipulation device which has an inlet channel, output channels, and a movable member formed on a substrate to sort one or more target particle from a sample stream. The system may include an interposer that receives the sorted particle and dispenses a carrier fluid with it to form a liquid droplet containing the particle. The droplet may then be dispensed to a microtiter plate, such that each well in the titer plate may contain a single target particle. The system may be used to separate individual biological cells, such as T cells, B cells, stem cells, cancer cells and sperm cells for further manipulation.

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Inventors:
FOSTER JOHN (US)
MARTINEZ NICHOLAS (US)
Application Number:
PCT/IB2015/053444
Publication Date:
January 14, 2016
Filing Date:
May 11, 2015
Export Citation:
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Assignee:
OWL BIOMEDICAL INC (US)
International Classes:
B01L3/00
Domestic Patent References:
WO2015132317A12015-09-11
Foreign References:
US20080261295A12008-10-23
US20120255373A12012-10-11
US20110030808A12011-02-10
US20140034555A12014-02-06
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