MENISCUS REGENERATION SUBSTRATE - EDUCATIONAL FOUNDATION OF OSAKA MEDICAL AND PHARMACEUTICAL UNIV

Title:

MENISCUS REGENERATION SUBSTRATE

Document Type and Number:

WIPO Patent Application WO/2018/221140

Kind Code:

A1

Abstract:

The purpose of the present invention is to provide a meniscus regeneration substrate which, when used to fill in defects in a meniscus of a knee joint in therapy to regenerate the meniscus, can promote regeneration of the meniscus. The present invention is a meniscus regeneration substrate which, when used to fill in defects in a meniscus of a knee joint in therapy to regenerate the meniscus, can promote regeneration of the meniscus, wherein: the meniscus regeneration substrate has a structure obtained by combining and integrating, in the stated order, a sponge layer composed of a bioabsorbable material that breaks down more slowly than polyglycolide, a nonwoven fabric layer composed of polyglycolide, and a sponge layer composed of a bioabsorbable material that breaks down more slowly than polyglycolide; the 50% compressive stress of the nonwoven fabric layer is 0.5 MPa or greater; and the nonwoven fabric layer has a thickness of 2 mm or greater.

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Inventors:

OTSUKI SHUHEI (JP)
INOUE TAE (JP)
SEZAKI SHUNSUKE (JP)

Application Number:

PCT/JP2018/017911

Publication Date:

December 06, 2018

Filing Date:

May 09, 2018

Export Citation:

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Assignee:

EDUCATIONAL FOUNDATION OF OSAKA MEDICAL AND PHARMACEUTICAL UNIV (JP)
GUNZE KK (JP)

International Classes:

A61L27/18; A61F2/38; A61L27/44; A61L27/50; A61L27/56; A61L27/58

Foreign References:

JP2005305163A	2005-11-04
JP2003512896A	2003-04-08
JP2006334430A	2006-12-14
JP2014183896A	2014-10-02
JPH0576586A	1993-03-30

Other References:

OOTSUKI, SHUHEI ET AL.: "Research on transplant of novel semilunar valve scaffold using mini pig", JOSKAS, vol. 42, no. 4, P2-71-6, 2 May 2017 (2017-05-02), pages 675
See also references of EP 3636292A4

Attorney, Agent or Firm:

YASUTOMI & ASSOCIATES (JP)

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