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Title:
MENTAL ILLNESS THERAPEUTIC AGENT HAVING IL-6 INHIBITOR AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2016/195088
Kind Code:
A1
Abstract:
Provided is a novel mental illness therapeutic agent. A mental illness therapeutic agent having an IL-6 inhibitor as an active ingredient.

Inventors:
KUNUGI HIROSHI (JP)
WAKABAYASHI CHISATO (JP)
Application Number:
PCT/JP2016/066638
Publication Date:
December 08, 2016
Filing Date:
June 03, 2016
Export Citation:
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Assignee:
NAT CENTER NEUROLOGY & PSYCHIATRY (JP)
CHUGAI PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K45/00; A61K39/395; A61P25/18; A61P43/00
Domestic Patent References:
WO2009052454A22009-04-23
WO2011149051A12011-12-01
Foreign References:
JP2015510513A2015-04-09
JP2012524112A2012-10-11
JP2014221815A2014-11-27
Other References:
MILLER B. J.: "An Open-label Trial of Adjunctive Tocilizumab in Schizophrenia", BIOLOGICAL PSYCHIATRY, vol. 75, no. 9, XP009507729
LIPINA T. V. ET AL.: "Maternal Immune Activation during Gestation Interacts with Disc1 Point Mutation to Exacerbate Schizophrenia-Related Behaviors in Mice", THE JOURNAL OF NEUROSCIENCE, vol. 33, no. 18, 1 May 2013 (2013-05-01), pages 7654 - 7666, XP055334459
SMITH S. E. P. ET AL.: "Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6", THE JOURNAL OF NEUROSCIENCE, vol. 27, no. 40, 3 October 2007 (2007-10-03), pages 10695 - 10702, XP055044947
See also references of EP 3305325A4
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
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