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Title:
MESENCHYMAL STEM CELL CULTURE FOR PREVENTION OR TREATMENT OF IMMUNE DISEASE OR INFLAMMATORY DISEASE AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/164467
Kind Code:
A1
Abstract:
The present invention relates to a mesenchymal stem cell culture for the prevention or treatment of immune diseases or inflammatory diseases and a preparation method thereof. Secreting the immunomodulator PGE2 at a high concentration and exhibiting an outstanding inhibitory effect on immune responses and the release of inflammatory cytokines, compared to stem cell cultures prepared in a two-dimensional manner according to conventional methods, the stem cell culture prepared by three-dimensionally culturing mesenchymal stem cells in a serum-free medium with the aid of a biocompatible scaffold in accordance with method of the present invention can be usefully used as a composition for preventing or treating immune diseases or inflammatory diseases.

Inventors:
LEE, Sung-Koo (405 NamsungPlaza, 130 Digital-ro,Geumcheon-gu, Seoul 153-782, 153-782, KR)
KIM, Mi-Hyung (405 NamsungPlaza, 130 Digital-ro,Geumcheon-gu, Seoul 153-782, 153-782, KR)
Application Number:
KR2016/009112
Publication Date:
September 28, 2017
Filing Date:
August 18, 2016
Export Citation:
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Assignee:
ANTEROGEN CO., LTD. (405 NamsungPlaza, 130 Digital-ro,Geumcheon-gu, Seoul 153-782, 153-782, KR)
International Classes:
C12N5/0775; A61K31/5575; A61K35/28; C12N5/00
Domestic Patent References:
WO2016029267A12016-03-03
Foreign References:
KR20150029280A2015-03-18
KR20160003512A2016-01-11
KR20120126284A2012-11-21
KR101189655B12012-10-11
Attorney, Agent or Firm:
KIM, Bo-min (4th Fl, 23 Baumoe-ro,Seocho-gu, Seoul, 06762, KR)
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