Title:
METAGENOMIC COMPOSITIONS AND METHODS FOR THE DETECTION OF BREAST CANCER
Document Type and Number:
WIPO Patent Application WO/2016/172179
Kind Code:
A3
Abstract:
The present invention provides compositions and methods for the detection of triple negative breast cancer. Compositions and methods are provided for detecting a metagenomic signature in a tissue sample from a subject that indicates the subject has triple negative breast cancer.
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Inventors:
ROBERTSON ERLE S (US)
ALWINE JAMES (US)
ALWINE JAMES (US)
Application Number:
PCT/US2016/028394
Publication Date:
December 15, 2016
Filing Date:
April 20, 2016
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
International Classes:
C12Q1/02; C12Q1/70; C12Q1/04; C12Q1/68; G01N33/50; G01N33/58
Foreign References:
| US20080199493A1 | 2008-08-21 | |||
| US20140296092A1 | 2014-10-02 |
Other References:
BALDWIN, DA ET AL.: "Metagenomic Assay for Identification of Microbial Pathogens in Tumor Tissues.", MBIO, 16 September 2014 (2014-09-16), XP055235333
PIANA, AF ET AL.: "HPV Infection and Triple-Negative Breast Cancers: An Italian Case-Control Study.", VIROLOGY JOURNAL., vol. 11, no. 190, 21 November 2014 (2014-11-21), pages 1 - 5, XP021204200
BANERJEE, S ET AL.: "Distinct Microbiological Signatures Associated With Triple Negative Breast Cancer.", SCIENTIFIC REPORTS., vol. 5, no. 15162, 15 October 2015 (2015-10-15), pages 1 - 14, XP055334059
PIANA, AF ET AL.: "HPV Infection and Triple-Negative Breast Cancers: An Italian Case-Control Study.", VIROLOGY JOURNAL., vol. 11, no. 190, 21 November 2014 (2014-11-21), pages 1 - 5, XP021204200
BANERJEE, S ET AL.: "Distinct Microbiological Signatures Associated With Triple Negative Breast Cancer.", SCIENTIFIC REPORTS., vol. 5, no. 15162, 15 October 2015 (2015-10-15), pages 1 - 14, XP055334059
Attorney, Agent or Firm:
DOYLE, Kathryn et al. (Centre Square West1500 Market Street, 38th Floo, Philadelphia Pennsylvania, US)
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