Title:
METAL-CARBOHYDRATE COMPLEX
Document Type and Number:
WIPO Patent Application WO/2021/201109
Kind Code:
A1
Abstract:
Provided is an L-glucose derivative represented by general formula (1). [In formula (1), X1 represents a -SAuR1 group, and X2, X3, X4, and X5 each independently represent a -OR2 group, a -NH2 group, or a fluorine atom. R1 represents a ligand, and R2 represents a hydrogen atom or an organic group.]
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Inventors:
YAMAGUCHI EIICHI (JP)
IIJIMA HIDEKI (JP)
IIJIMA HIDEKI (JP)
Application Number:
PCT/JP2021/013857
Publication Date:
October 07, 2021
Filing Date:
March 31, 2021
Export Citation:
Assignee:
ORBIO CORP (JP)
International Classes:
C07H23/00; A61K31/7135; A61K41/00; A61P35/00; C07F1/12; C07F9/50; C07F19/00
Domestic Patent References:
| WO2012133688A1 | 2012-10-04 |
Foreign References:
| US5624908A | 1997-04-29 | |||
| JP2021501832A | 2021-01-21 | |||
| JP2007536016A | 2007-12-13 |
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NAVARRO, M. ET AL.: "Metal-chloroquine derivatives as possible anti-malarial drugs: evaluation of anti-malarial activity and mode of action", MALARIA JOURNAL, vol. 13, no. 471, 3 December 2014 (2014-12-03), pages 1 - 8, XP021204957, DOI: 10.1186/1475-2875-13-471
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SUTTON B.M. ET AL., J. MED. CHEM., vol. 15, 1972, pages 1095 - 98
WU, B. ET AL., J. MED. CHEM., vol. 62, 2019, pages 7751 - 68
KILLOCK, D, NATURE REVIEWS CLINICAL ONCOLOGY, vol. 15, 2018, pages 266
ONO K. ET AL., CANCERS, vol. 12, 2020, pages 850
GREEN CHEMISTRY, vol. 17, no. 4, 2015, pages 2545 - 2551
MIYAZAKI J. ET AL., ENDOCRINOLOGY, vol. 127, 1990, pages 126 - 132
YAMATO, E. ET AL., PLOS ONE, vol. 8, 2013, pages e61211
SASAKI, A. ET AL., HUMAN CELL, vol. 29, 2016, pages 37 - 45
SUTTON B.M. ET AL., J. MED. CHEM., vol. 15, 1972, pages 1095 - 98
WU, B. ET AL., J. MED. CHEM., vol. 62, 2019, pages 7751 - 68
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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