Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METAL COMPLEXES OF N-HETEROCYCLIC CARBENES AS RADIOPHARMACEUTICALS AND ANTIBIOTICS
Document Type and Number:
WIPO Patent Application WO2005023760
Kind Code:
A3
Abstract:
A method for inhibiting microbial growth comprises administering an effective amount of a silver complex of a N-heterocyclic amine. A method for treating cancer cells or a method for imaging one or more tissues of a patient includes administering an effective amount of a complex of a N-heterocyclic amine and a radioactive metal. N-heterocyclic carbenes of the present invention may be represented by formula (I) wherein Z is a heterocyclic group, and R1 and R2 are, independently or in combination, hydrogen or a C1-C12 organic group selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, arylalkyl, alkylaryl, heterocyclic, and alkoxy groups and substituted derivatives thereof.

Inventors:
YOUNGS WILEY J (US)
TESSIER CLAIRE A (US)
GARRISON JARED (US)
QUEZADA CAROL (US)
MELAIYE ABDULKAREEM (US)
PANZNER MATHEW (US)
DURMAS SEMIH (US)
AYSEGUL KASCATAN-NEBIOGLU (US)
Application Number:
PCT/US2004/029285
Publication Date:
October 12, 2006
Filing Date:
September 07, 2004
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV AKRON (US)
YOUNGS WILEY J (US)
TESSIER CLAIRE A (US)
GARRISON JARED (US)
QUEZADA CAROL (US)
MELAIYE ABDULKAREEM (US)
PANZNER MATHEW (US)
DURMAS SEMIH (US)
AYSEGUL KASCATAN-NEBIOGLU (US)
International Classes:
C07D487/22; C07D401/14; C07D403/14; C07D471/22; C07D487/04; C07F1/00; C07D
Foreign References:
US6919448B22005-07-19
US6794327B22004-09-21
US6288197B12001-09-11
Other References:
See also references of EP 1660444A4
Download PDF: