METAL SALTS OF (3S)-3-METHOXYCARBONYL-4-PHENYLBUTYRIC ACID AND USAGE THEREOF

Title:

METAL SALTS OF (3S)-3-METHOXYCARBONYL-4-PHENYLBUTYRIC ACID AND USAGE THEREOF

Document Type and Number:

WIPO Patent Application WO/2003/062186

Kind Code:

A1

Abstract:

Novel metal salts of (3S)-3-methoxycarbonyl-4-phenyl- butyric acid represented by the general formula (&Igr ) and being useful as intermediates in the production of various drugs: (&Igr ) [wherein M is a sodium ion or a calcium ion; when M is a sodium ion, n is 1, while when M is a calcium ion, n is 2]; and a process for preparation of the benzylsuccinic acid derivative (A) and pharmacologically acceptable salts thereof, which exhibit insulin secretion promoting and blood sugar decreasing effects and are useful as diabetes remedies, by using the above salt as the intermediate.

Inventors:

YANAGI TAKASHI (JP)
KIKUCHI KEN (JP)

Application Number:

PCT/JP2003/000341

Publication Date:

July 31, 2003

Filing Date:

January 17, 2003

Export Citation:

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Assignee:

KISSEI PHARMACEUTICAL (JP)
YANAGI TAKASHI (JP)
KIKUCHI KEN (JP)

International Classes:

A61K31/4035; A61P3/10; C07C69/612; C07D209/44; (IPC1-7): C07C69/612; A61K31/4035; A61P3/10; C07D209/44

Foreign References:

JP2001261644A	2001-09-26
JP2001261645A	2001-09-26

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