Title:
METALLOPROTEASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2006/009325
Kind Code:
A1
Abstract:
A J5 inhibitor containing a compound represented by the general formula (I): (wherein the symbols have the same meanings as in the description), a salt thereof, a solvate of either, or a prodrug of any of these. The compound having J5 inhibitory activity can be used for the prevention and/or treatment of inflammatory diseases, autoimmune diseases, allergic diseases, and skin diseases.
Inventors:
HABASHITA HIROMU (JP)
SHIBAYAMA SHIRO (JP)
MATSUO MASAYOSHI (JP)
SHIBAYAMA SHIRO (JP)
MATSUO MASAYOSHI (JP)
Application Number:
PCT/JP2005/013900
Publication Date:
January 26, 2006
Filing Date:
July 22, 2005
Export Citation:
Assignee:
ONO PHARMACEUTICAL CO (JP)
HABASHITA HIROMU (JP)
SHIBAYAMA SHIRO (JP)
MATSUO MASAYOSHI (JP)
HABASHITA HIROMU (JP)
SHIBAYAMA SHIRO (JP)
MATSUO MASAYOSHI (JP)
International Classes:
A61K31/401; A61K31/4025; A61K31/4045; A61K31/405; A61K31/4178; A61K38/00; A61P17/00; A61P29/00; A61P37/02; A61P37/08; A61P43/00; G01N33/15; G01N33/50; C07D207/16; C07D403/06
Domestic Patent References:
| WO2003084941A2 | 2003-10-16 |
Foreign References:
| JP2003521437A | 2003-07-15 | |||
| US20040077552A1 | 2004-04-22 | |||
| JPH05508163A | 1993-11-18 |
Other References:
MUELLER C. ET AL.: "Mannose Receptor Ligand-Positive Cells Express the Metalloprotease Decysin in the B Cell Follicle.", THE JOURNAL OF IMMUNOLOGY, vol. 167, 2001, pages 5052 - 5060, XP002993091
Attorney, Agent or Firm:
Ohie, Kunihisa (Selva-Ningyocho 6F 14-6, Nihonbashi-Ningyocho 2-chom, Chuo-ku Tokyo, JP)
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