Title:
METHOD FOR ACTIVATING PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR- gamma
Document Type and Number:
WIPO Patent Application WO2001098536
Kind Code:
A3
Abstract:
The invention relates to a method of identifying nuclear receptor controlled genes in specific tissues. In particular, the method also provides a method of activating PPAR gamma nuclear receptor controlled target genes in vivo in a tissue-specific manner.
Inventors:
FORMAN BARRY M
Application Number:
PCT/US2001/019229
Publication Date:
June 27, 2002
Filing Date:
June 15, 2001
Export Citation:
Assignee:
HOPE CITY (US)
International Classes:
A01K67/027; A61K38/00; A61K48/00; A61P3/10; C07K14/705; C12N5/10; C12N15/09; C12N15/85; C12Q1/68; (IPC1-7): C07K14/705; A01K67/027; C07K14/35; C12N15/63; C12Q1/68
Domestic Patent References:
| WO2001042290A2 | 2001-06-14 | |||
| WO2000029846A2 | 2000-05-25 | |||
| WO2000017334A2 | 2000-03-30 |
Foreign References:
| US5919667A | 1999-07-06 |
Other References:
REUSCH J E B ET AL: "CREB ACTIVATION INDUCES ADIPOGENESIS IN 3T3-L1 CELLS", MOLECULAR AND CELLULAR BIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US, vol. 20, no. 3, February 2000 (2000-02-01), pages 1008 - 1020, XP002939211, ISSN: 0270-7306
BERGER J ET AL.: "Thiazolidinediones produce a conformational change in peroxisomal proliferator-activator receptor-gamma : binding and activation correlate with antidiabetic actions in db/db mice", ENDOCRINOLOGY, vol. 137, no. 10, October 1996 (1996-10-01), BALTIMORE, MD., US, pages 4189 - 4195, XP001064610, ISSN: 0013-7227
See also references of EP 1294761A2
BERGER J ET AL.: "Thiazolidinediones produce a conformational change in peroxisomal proliferator-activator receptor-gamma : binding and activation correlate with antidiabetic actions in db/db mice", ENDOCRINOLOGY, vol. 137, no. 10, October 1996 (1996-10-01), BALTIMORE, MD., US, pages 4189 - 4195, XP001064610, ISSN: 0013-7227
See also references of EP 1294761A2
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