METHOD OF ACTIVATING TUMOR-INFILTRATING LYMPHOCYTES (TILS)

Title:

METHOD OF ACTIVATING TUMOR-INFILTRATING LYMPHOCYTES (TILS)

Document Type and Number:

WIPO Patent Application WO/2019/137384

Kind Code:

A1

Abstract:

A method for activating tumor-infiltrating lymphocytes (TILs) in a subject in need is provided, particularly by administering to the subject a fermented composition generated via fermentation of symbiotic microbiota in a medium.

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Inventors:

LU KUNG-MING (CN)
KUO MIN-LIANG (CN)
YANG AI-JEN (CN)

Application Number:

PCT/CN2019/070944

Publication Date:

July 18, 2019

Filing Date:

January 09, 2019

Export Citation:

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Assignee:

MICROBIO CO LTD (CN)

International Classes:

A61K35/744; A61K36/06; A61K36/48; A61K39/395; A61P35/00

Domestic Patent References:

WO2017167213A1

2017-10-05

Foreign References:

CN1375314A	2002-10-23
CN104415298A	2015-03-18
CN1720954A	2006-01-18
TWI252759B	2006-04-11

Other References:

ARAGON F. ET AL.: "Inhibition of Growth and Metastasis of Breast Cancer in Mice by Milk Fermented With Lactobacillus casei CRL 431", J. IMMUNOTHER, vol. 38, no. 5, 30 June 2015 (2015-06-30), pages 185 - 196, XP055626059
See also references of EP 3737395A4

Attorney, Agent or Firm:

GE CHENG & CO., LTD. (CN)

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