Title:
METHOD FOR ANALYZING BASE SEQUENCE AND GENE ANALYZER
Document Type and Number:
WIPO Patent Application WO/2023/195077
Kind Code:
A1
Abstract:
A gene analyzer that: obtains phoretic data which is time-series data of the signal intensity of multiple frequencies obtained by electrophoresing a sample; by using the phoretic data, identifies a single fluorescence spectral time at which a single fluorescence spectrum, a spectrum derived from only one base, is present; calculates a spectral shift model by using a spectrum obtained from a color transformation matrix at the single fluorescence spectral time and the single fluorescence spectrum at the single fluorescence spectral time; corrects the phoretic data by using the spectral shift model; and identifies the base sequence of the sample by using the corrected phoretic data.
Inventors:
YOKOYAMA TORU (JP)
YAMAZAKI MOTOHIRO (JP)
KATO HIROKAZU (JP)
SUMIDA NORIYUKI (JP)
YAMAZAKI MOTOHIRO (JP)
KATO HIROKAZU (JP)
SUMIDA NORIYUKI (JP)
Application Number:
PCT/JP2022/017118
Publication Date:
October 12, 2023
Filing Date:
April 05, 2022
Export Citation:
Assignee:
HITACHI HIGH TECH CORP (JP)
International Classes:
C12Q1/6869; C12M1/00; G01N21/64
Foreign References:
| JP2014117222A | 2014-06-30 | |||
| JP2020041876A | 2020-03-19 | |||
| JP2020510822A | 2020-04-09 | |||
| JP2006208060A | 2006-08-10 |
Other References:
LI LEI: "DNA SEQUENCING AND PARAMETRIC DECONVOLUTION", STATISTICA SINICA, vol. 12, no. 1, 1 January 2002 (2002-01-01), pages 179 - 202, XP093098001, ISSN: 1017-0405
Attorney, Agent or Firm:
TOU-OU PATENT FIRM (JP)
Download PDF:
Previous Patent: ELECTRIC MOTOR, BLOWER, AND AIR CONDITIONING DEVICE
Next Patent: POWER ADJUSTMENT DEVICE AND POWER ADJUSTMENT CONTROL PROGRAM
Next Patent: POWER ADJUSTMENT DEVICE AND POWER ADJUSTMENT CONTROL PROGRAM