Title:
METHOD FOR ANALYZING INFORMATION FOR DIAGNOSIS AND KIT THEREFOR
Document Type and Number:
WIPO Patent Application WO/2015/097862
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a novel method for analyzing information for diagnosis, whereby prostate cancer can be distinguished from a benign prostate disease at a high accuracy, and a kit for diagnosis to be used for acquiring the diagnostic information. One embodiment of the method for analyzing information for diagnosis according to the present invention is a method for analyzing information for diagnosis that comprises: measuring the concentration of mucin-1 (Tn-MUC1) having reactivity with a lectin, said lectin being capable of recognizing an N-acetyl-D-galactosamine→serine (threonine) residue and binding thereto, in a blood sample collected from a subject to be diagnosed; comparing the measured value with a threshold; and, when the measured mucin-1 concentration is higher than the threshold, it is estimated that the subject suffers not from prostate cancer but from a benign prostate disease. One embodiment of the kit for diagnosis according to the present invention is a kit for diagnosis that comprises an anti-mucin-1 antibody for treating Tn-MUC1 and a lectin for detection, said lectin being capable of recognizing an N-acetyl-D-galactosamine→serine (threonine) residue and binding thereto.
Inventors:
YAMASHITA KATSUKO (JP)
KAYA TAKATOSHI (JP)
IDE YOUICHI (JP)
KANEKO TOMONORI (JP)
KAYA TAKATOSHI (JP)
IDE YOUICHI (JP)
KANEKO TOMONORI (JP)
Application Number:
PCT/JP2013/085115
Publication Date:
July 02, 2015
Filing Date:
December 27, 2013
Export Citation:
Assignee:
KONICA MINOLTA INC (JP)
International Classes:
G01N33/68; G01N33/53
Domestic Patent References:
| WO2010100862A1 | 2010-09-10 | |||
| WO2012173228A1 | 2012-12-20 | |||
| WO2010090264A1 | 2010-08-12 | |||
| WO2011135869A1 | 2011-11-03 |
Foreign References:
| JP5231247B2 | 2013-07-10 | |||
| JP2009535051A | 2009-10-01 | |||
| JP2013526852A | 2013-06-27 | |||
| JP2013076666A | 2013-04-25 |
Other References:
KUNO ATSUSHI ET AL.: "Wisteria floribunda agglutinin-positive mucin 1 is a sensitive biliary marker for human cholangiocarcinoma", HEPATOLOGY, vol. 52, no. 1, 2010, pages 174 - 182, XP055030660
Attorney, Agent or Firm:
SSINPAT PATENT FIRM (JP)
Patent business corporation SSINPAT (JP)
Patent business corporation SSINPAT (JP)
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