Title:
METHOD AND APPARATUS FOR DETECTING HAZARDOUS AGENTS
Document Type and Number:
WIPO Patent Application WO1999060371
Kind Code:
A3
Abstract:
A method and apparatus for determining the presence of a toxic agent, such as a toxic chemical, bacterium, or virus is described. In one embodiment, the apparatus includes a sampler that comprises means for extracting a sample from the environment of the apparatus, such as the ambient atmosphere, water, or soil. Optionally, the sampler can include additional pre-processing means to isolate particular elements of the sample or put the sample in better condition for assay. The apparatus and method can be used to detect a variety of chemical and biological toxins, both natural and non-natural, including chemical and biological toxins of unknown composition and origin.
Inventors:
OKARMA THOMAS
GOLD JOSEPH
MURAI JAMES
GOLD JOSEPH
MURAI JAMES
Application Number:
PCT/US1999/010770
Publication Date:
February 10, 2000
Filing Date:
May 14, 1999
Export Citation:
Assignee:
GERON CORP (US)
International Classes:
G01N33/50; (IPC1-7): C12Q1/70; C12M3/00; G01N33/569
Foreign References:
| US5661035A | 1997-08-26 | |||
| US5660986A | 1997-08-26 |
Other References:
SEHLMEYER ET AL: "Primordial Germ Cell-derived Embryonic Germ Cells of the Mouse-In Vitro Model for Cytotoxicity Studies with Chemical Mutagens", TOXICOLOGY IN VITRO., vol. 10, 1996, pages 755 - 763, XP002923261
WOBUS ET AL: "In Vitro Cellular Models for Cardiac Development and Pharmacotoxicology", TOXICOLOGY IN VITRO., vol. 9, no. 4, pages 477 - 488, XP002923262
STEGMANN ET AL: "Membrane Fusion Activity of Influenza Virus. Effects of Gangliosides and Negatively Charged Phospholipids in Target Liposomes", BIOCHEMISTRY, vol. 28, 1989, pages 1698 - 1704, XP002923263
DATABASE MEDLINE ON DIALOG, CAMILLERI ET AL: "Validity of a Model of cultured Myocardial Cells for Assessment of Cardioplegia"
HARLE-BACHOR ET AL: "Telomerase Activity in the Regenerative Basal Layer of the Epidermis in Human Skin and in Immortal and Carcinoma-Derived Skin Keratinocytes", PROC. NATL. ACAD. SCI. USA,, vol. 93, June 1996 (1996-06-01), pages 6476 - 6481, XP002923264
WOBUS ET AL: "In Vitro Cellular Models for Cardiac Development and Pharmacotoxicology", TOXICOLOGY IN VITRO., vol. 9, no. 4, pages 477 - 488, XP002923262
STEGMANN ET AL: "Membrane Fusion Activity of Influenza Virus. Effects of Gangliosides and Negatively Charged Phospholipids in Target Liposomes", BIOCHEMISTRY, vol. 28, 1989, pages 1698 - 1704, XP002923263
DATABASE MEDLINE ON DIALOG, CAMILLERI ET AL: "Validity of a Model of cultured Myocardial Cells for Assessment of Cardioplegia"
HARLE-BACHOR ET AL: "Telomerase Activity in the Regenerative Basal Layer of the Epidermis in Human Skin and in Immortal and Carcinoma-Derived Skin Keratinocytes", PROC. NATL. ACAD. SCI. USA,, vol. 93, June 1996 (1996-06-01), pages 6476 - 6481, XP002923264
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