Title:
METHOD AND APPARATUS FOR DEVELOPING DNA MICROARRAYS
Document Type and Number:
WIPO Patent Application WO2001057254
Kind Code:
A3
Abstract:
The invention relates to methods and systems for high throughput and quantitative processing, assaying and development of microarrays of DNA, proteins and other biological and chemical reagents. An in-line processing system (100) can be utilized based on a continuous indexing of microarray slides or substrates (130) through a series of processes where different functions or processes are performed at different positions on a conveyor (122). A batch processing system (200) can also be utilized, wherein the process steps are performed serially to an array of microarray slides or substrates (130) mounted on a movable table or carriage (222). A versatile positive displacement aerosol dispensing system (10) has the ability to aspirate fluid. A universal substrate cassette (310) can hold a plurality of substrates or slides (130) through a number of process steps without the need to remove the substrates or slides (130) from the cassette (310).
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Inventors:
TISONE THOMAS C
ROSE DONALD J JR
CABOURNE MICHAEL K
ROSE DONALD J JR
CABOURNE MICHAEL K
Application Number:
PCT/US2001/003344
Publication Date:
December 06, 2001
Filing Date:
February 02, 2001
Export Citation:
Assignee:
CARTESIAN TECHNOLOGIES INC (US)
International Classes:
B01J19/00; G01N35/02; C40B40/06; C40B60/14; C40B70/00; G01N1/31; G01N35/10; (IPC1-7): B01J19/00; G01N35/02
Domestic Patent References:
| WO1997022882A1 | 1997-06-26 | |||
| WO1998047006A1 | 1998-10-22 | |||
| WO1999044062A1 | 1999-09-02 | |||
| WO1998058745A1 | 1998-12-30 | |||
| WO1999034931A1 | 1999-07-15 |
Foreign References:
| US5985214A | 1999-11-16 |
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