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Title:
METHOD AND APPARATUS FOR MEASURING SURFACTANT CRITICAL MICELLE CONCENTRATION
Document Type and Number:
WIPO Patent Application WO/2019/080076
Kind Code:
A1
Abstract:
Provided is a method for measuring surfactant critical micelle concentration, specifically: measuring the chemiluminescence value of an acridine compound as a luminescent agent in a series of concentrations of a surfactant solution; according to a logarithmic values of the obtained luminescence value and logarithmic values corresponding to the surfactant concentrations in the surfactant solution, linear fitting is performed to obtain a plurality of fitting straight lines; the minimum value of the surfactant concentration corresponding to the intersection of two adjacent fitting lines is the critical micelle concentration of that surfactant. The sensitivity of the method is high, measurement results are accurate, detection costs are low, operation is simple, and testing is fast and efficient, and the critical micelle concentration of the surfactant can be obtained in only a few minutes per test. Also provided is an apparatus for measuring surfactant critical micelle concentration.

Inventors:
ZHANG NANA (CN)
WANG XIAOYAN (CN)
WEI CHUNYAO (CN)
XU TENG (CN)
Application Number:
PCT/CN2017/107929
Publication Date:
May 02, 2019
Filing Date:
October 27, 2017
Export Citation:
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Assignee:
SUZHOU HYBIOME BIOMEDICAL ENG CO LTD (CN)
International Classes:
G01N21/76
Foreign References:
CN104897628A2015-09-09
CN103411961A2013-11-27
Other References:
LV , XIAOHU ET AL.: "Non-official translation: Determination of the CMC of Surfactants by Chemiluminescence Method", CHINA SURFACTANT DETERGENT & COSMETICS, 31 December 1990 (1990-12-31), ISSN: 1001-1803
LIN, XUCONG ET AL.: "Recent Developments of Chemiluminescence Reagents", WORLD SCI-TECH R & D, vol. 26, no. 4, 31 August 2004 (2004-08-31), pages 136 - 143, ISSN: 1006-6055
NATRAJAN, A. ET AL.: "Effect of Surfactants on the Chemiluminescence of Acridinium Dimethylphenyl Ester Labels and Their Conjugates", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, no. 14, 31 December 2011 (2011-12-31), pages 5092 - 5103, XP055314612, DOI: doi:10.1039/c1ob05543g
ZHAO, DANHUA ET ET AL.: "Flow-Injection Chemiluminescence Method for the Determination of Critical Micelle Concentration of Cetyltrimethylammonium", CHINESE JOURNAL OF ANALYSIS LABORATORY, vol. 22, no. 2, 31 March 2003 (2003-03-31), pages 77 - 79, ISSN: 1000-0720
Attorney, Agent or Firm:
SUZHOU ZHITU INTELLECTUAL PROPERTY FIRM (CN)
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