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Title:
METHOD AND APPARATUS FOR SIMULTANEOUSLY MANUFACTURING ULTRA PURE BETULIN AND HIGHLY PURE BETULINIC ACID FROM BIRCH BARK
Document Type and Number:
WIPO Patent Application WO/2011/074766
Kind Code:
A2
Abstract:
The present invention relates to a method and apparatus for simultaneously manufacturing ultra pure betulin and highly pure betulinic acid from birch bark, which employ a technique of: using a polar organic solvent to obtain a crude extract containing a betulin content of 70 to 83% and a betulinic acid content of 4 to 8% from the outer bark and inner bark of birch trees that grow naturally in northern hemisphere regions at a northern latitude of 34° or greater, such as in South Korea, China, North America, and Europe; and using a single or mixed polar solvent to obtain a crystallized highly pure betulin with a purity of 95% or greater, wherein ultra pure betulin with a purity of 99.5% or greater and highly pure betulinic acid with a purity of 95% or greater can be simultaneously produced from the crystallized product.

Inventors:
CHUE, Kuck-Tack (4 EXPO APT, Jeonmin-Dong Yuseong-Gu, Daejeon 305-762, 305-762, KR)
주국택 (대전광역시 유성구 전민동 엑스포아파트, 305-762 Daejeon, 305-762, KR)
PARK, Jong-Kee (308-504, Yeulmaemayul APT. Jijok-Dong, Yuseong-Gu, Daejeon 305-769, 305-769, KR)
박종기 (대전광역시 유성구 지족동 열매마을아파트 308-504, 305-769 Daejeon, 305-769, KR)
Application Number:
KR2010/006329
Publication Date:
June 23, 2011
Filing Date:
September 16, 2010
Export Citation:
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Assignee:
KOREA INSTITUTE OF ENERGY RESEARCH (71-2, Jang-Dong Yuseong-Gu, Daejeon 305-343, 305-343, KR)
한국에너지기술연구원 (대전광역시 유성구 장동 71-2, 305-343 Daejeon, 305-343, KR)
CHUE, Kuck-Tack (4 EXPO APT, Jeonmin-Dong Yuseong-Gu, Daejeon 305-762, 305-762, KR)
주국택 (대전광역시 유성구 전민동 엑스포아파트, 305-762 Daejeon, 305-762, KR)
PARK, Jong-Kee (308-504, Yeulmaemayul APT. Jijok-Dong, Yuseong-Gu, Daejeon 305-769, 305-769, KR)
International Classes:
A61K36/185; B01D9/00; B01D11/00
Attorney, Agent or Firm:
CHANG, Soon-Boo et al. (B-812 Woolim Lion's Valley, 371-28 Gasan-dong,Geumcheon-gu, Seoul 153-803, 153-803, KR)
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