Title:
METHOD OF ASSESSING EFFECTIVENESS OF INTERFERON THERAPY AND KIT FOR ASSESSING THE SAME
Document Type and Number:
WIPO Patent Application WO/2006/107078
Kind Code:
A1
Abstract:
The effectiveness of interferon therapy is assessed in advance. By using the concentration of a marker substance in the body fluid of a patient as an indicator, it is assessed whether or not interferon therapy is effective for the patient. A method of measuring the concentration of a marker substance can be carried out by entrapping the marker substance in a carrier such as a substrate having an ion exchanger or a metal chelator immobilized thereon and performing mass spectrometry. With the use of a kit for assessing the effectiveness of interferon therapy comprising a carrier having a substance with affinity for the marker substance immobilized thereon, it can be more simply and promptly assessed whether or not the interferon therapy is effective.
Inventors:
Arikuni, Hisashi c/o Kyoto Prefectural University of Medicine (465Kajii-cho, Kawaramachidori-Hirokoji, Agaru,
Kamigyo-ku, Kyoto-sh, Kyoto 66, 60285, JP)
Yoshikawa, Toshikazu c/o Kyoto Prefectural University of Medicine (465Kajii-cho, Kawaramachidori-Hirokoji, Agaru, Kamigyo-ku, Kyoto-sh, Kyoto 66, 60285, JP)
Ooki, Toshichika c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Aoki, Motohide (201 17-17, Kamitsuruma 4-chome Sagamihara-sh, Kanagawa 18, 22808, JP)
Kigawa, Eri c/o Biomarker Science Co. (Ltd 2-8, Honmachibashi, Chuo-ku, Osaka-sh, Osaka 29, 54000, JP)
Yamaguchi, Tsugihisa c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Mafune, Syouichi c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Takahashi, Yutaka c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Yoshikawa, Toshikazu c/o Kyoto Prefectural University of Medicine (465Kajii-cho, Kawaramachidori-Hirokoji, Agaru, Kamigyo-ku, Kyoto-sh, Kyoto 66, 60285, JP)
Ooki, Toshichika c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Aoki, Motohide (201 17-17, Kamitsuruma 4-chome Sagamihara-sh, Kanagawa 18, 22808, JP)
Kigawa, Eri c/o Biomarker Science Co. (Ltd 2-8, Honmachibashi, Chuo-ku, Osaka-sh, Osaka 29, 54000, JP)
Yamaguchi, Tsugihisa c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Mafune, Syouichi c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Takahashi, Yutaka c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Application Number:
PCT/JP2006/307254
Publication Date:
October 12, 2006
Filing Date:
April 05, 2006
Export Citation:
Assignee:
BIOMARKER SCIENCE CO., LTD (2-8 Honmachibashi, Chuo-ku Osaka-sh, Osaka 29, 54000, JP)
Arikuni, Hisashi c/o Kyoto Prefectural University of Medicine (465Kajii-cho, Kawaramachidori-Hirokoji, Agaru, Kamigyo-ku, Kyoto-sh, Kyoto 66, 60285, JP)
Yoshikawa, Toshikazu c/o Kyoto Prefectural University of Medicine (465Kajii-cho, Kawaramachidori-Hirokoji, Agaru, Kamigyo-ku, Kyoto-sh, Kyoto 66, 60285, JP)
Ooki, Toshichika c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Aoki, Motohide (201 17-17, Kamitsuruma 4-chome Sagamihara-sh, Kanagawa 18, 22808, JP)
Kigawa, Eri c/o Biomarker Science Co. (Ltd 2-8, Honmachibashi, Chuo-ku, Osaka-sh, Osaka 29, 54000, JP)
Yamaguchi, Tsugihisa c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Mafune, Syouichi c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Takahashi, Yutaka c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Arikuni, Hisashi c/o Kyoto Prefectural University of Medicine (465Kajii-cho, Kawaramachidori-Hirokoji, Agaru, Kamigyo-ku, Kyoto-sh, Kyoto 66, 60285, JP)
Yoshikawa, Toshikazu c/o Kyoto Prefectural University of Medicine (465Kajii-cho, Kawaramachidori-Hirokoji, Agaru, Kamigyo-ku, Kyoto-sh, Kyoto 66, 60285, JP)
Ooki, Toshichika c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Aoki, Motohide (201 17-17, Kamitsuruma 4-chome Sagamihara-sh, Kanagawa 18, 22808, JP)
Kigawa, Eri c/o Biomarker Science Co. (Ltd 2-8, Honmachibashi, Chuo-ku, Osaka-sh, Osaka 29, 54000, JP)
Yamaguchi, Tsugihisa c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Mafune, Syouichi c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
Takahashi, Yutaka c/o Biomarker Science Co. (Ltd Kyoto Katsura Laboratory 1-36, Goryoohara, Nishikyo-ku, Kyoto-sh, Kyoto 45, 61582, JP)
International Classes:
G01N33/50; G01N27/62; G01N33/15; G01N33/68; G01N33/50; G01N27/62; G01N33/15; G01N33/68
Attorney, Agent or Firm:
Oshio, Takeshi (Fifteenth Floor, Crystal Tower 2-27, Shiromi 1-chome, Chuo-ku, Osaka-sh, Osaka 15, 54060, JP)
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