Title:
METHOD BY WHICH BRAIN WITH ALZHEIMER'S DISEASE RECOVERS FROM BRAIN WAVE DAMAGE BY USING OPTOGENETICS
Document Type and Number:
WIPO Patent Application WO/2021/132903
Kind Code:
A1
Abstract:
The present invention relates to a method by which a brain with Alzheimer's disease recovers from brain wave damage by using optogenetics. The method by which a brain with Alzheimer's disease recovers from brain wave damage, of the present invention, does not directly damage neurons through photostimulation instead of electrostimulation, and uses optogenetics so as to specify inhibitory neurons related to brain wave damage caused by Alzheimer's disease, and then selectively use light through optogenetics so as to regulate the activity of damaged neurons, thereby enabling a brain with Alzheimer's disease to recover from damaged brain waves to a normal level.
Inventors:
KWAG JEEHYUN (KR)
PARK KYERL (KR)
CHUNG HYOWON (KR)
PARK KYERL (KR)
CHUNG HYOWON (KR)
Application Number:
PCT/KR2020/016765
Publication Date:
July 01, 2021
Filing Date:
November 25, 2020
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
A61N5/06; A61M21/00
Foreign References:
| JP2012187140A | 2012-10-04 | |||
| KR20190058383A | 2019-05-29 | |||
| KR101906577B1 | 2018-10-10 |
Other References:
CHUNG HYOWON, PARK KYERL, JANG HYUN JAE, KOHL MICHAEL M, KWAG JEEHYUN: "Optogenetic activation of SST-positive interneurons restores hippocampal theta oscillation impairment induced by soluble amyloid beta oligomers in vivo", BIORXIV, 7 November 2018 (2018-11-07), XP055824420, DOI: 10.1101/465112
KIM TAE-NEUNG: "Overview of R&D tasks", 2017 RESEARCH INSTITUTE'S UNIQUE TASK RESULT REPORT, 1 January 2018 (2018-01-01), Korea, pages 1 - 11, XP009528873
KIM TAE-NEUNG: "Overview of R&D tasks", 2017 RESEARCH INSTITUTE'S UNIQUE TASK RESULT REPORT, 1 January 2018 (2018-01-01), Korea, pages 1 - 11, XP009528873
Attorney, Agent or Firm:
YUN, Kuisang (KR)
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