Title:
METHOD FOR CARBOXYLATION OF SILK PROTEIN AND CARBOXYLATED SILK PROTEIN PREPARED BY METHOD AND APPLICATION OF CARBOXYLATED SILK PROTEIN
Document Type and Number:
WIPO Patent Application WO/2022/252974
Kind Code:
A1
Abstract:
The present invention relates to a method for carboxylation of a silk protein and a carboxylated silk protein prepared by the method and an application of the carboxylated silk protein. The method for carboxylation of a silk protein provided by the present invention comprises the step of enabling the silk protein to react with dicarboxylic acid anhydride in the presence of a lithium salt. Compared with silk protein carboxylation methods in the prior art, the method of the present invention has the advantages of mild preparation conditions and simple preparation steps; moreover, compared with an uncarboxylated silk protein, the carboxylated silk protein prepared in the present invention has no decreased molecular weight, and shows improved hydrophilicity.
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Inventors:
GUO CHENGCHEN (CN)
SUN ZIYANG (CN)
SUN ZIYANG (CN)
Application Number:
PCT/CN2022/093191
Publication Date:
December 08, 2022
Filing Date:
May 17, 2022
Export Citation:
Assignee:
UNIV WESTLAKE (CN)
International Classes:
C08H1/00
Foreign References:
| JP2012136795A | 2012-07-19 | |||
| JP2011024449A | 2011-02-10 | |||
| CN112773942A | 2021-05-11 | |||
| JPH11228837A | 1999-08-24 |
Other References:
ZHANG, CENG: "Research Progress on Chemical Modification of Silk Fibroin", MODERN SILK SCIENCE & TECHNOLOGY, vol. 27, no. 5, 28 October 2012 (2012-10-28), pages 208 - 212, XP009541760, ISSN: 1674-8433
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (CN)
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