Title:
METHOD FOR CARRYING OUT SEQUENTIAL REACTIONS USING A HEATING MEDIUM HEATED BY MEANS OF INDUCTION
Document Type and Number:
WIPO Patent Application WO/2011/045091
Kind Code:
A3
Abstract:
The invention relates to a method for carrying out at least two successive chemical reactions for producing a target compound from at least one first and at least one second and/or further reactants, comprising a first reaction and a further reaction in a reactor containing a reaction medium, wherein the reaction medium in the reactor is brought in contact with a solid heating medium that can be heated by means of electromagnetic induction and that is located inside the reactor and surrounded by the reaction medium. The heating medium is heated by means of electromagnetic induction using an inductor, wherein in a first reaction, an intermediate compound is formed, from which in a further reaction the target compound is generated. Between the first and the further reactions, at least one reactant that was not present in the reactor before the first reaction is added to the reactor. The target compound is separated from the heating medium.
Inventors:
FRIESE CARSTEN (DE)
KIRSCHNING ANDREAS (DE)
CEYLAN SASCHA VOLKAN (DE)
WEGNER JENS (DE)
KIRSCHNING ANDREAS (DE)
CEYLAN SASCHA VOLKAN (DE)
WEGNER JENS (DE)
Application Number:
PCT/EP2010/059213
Publication Date:
August 11, 2011
Filing Date:
June 29, 2010
Export Citation:
Assignee:
HENKEL AG & CO KGAA (DE)
FRIESE CARSTEN (DE)
KIRSCHNING ANDREAS (DE)
CEYLAN SASCHA VOLKAN (DE)
WEGNER JENS (DE)
FRIESE CARSTEN (DE)
KIRSCHNING ANDREAS (DE)
CEYLAN SASCHA VOLKAN (DE)
WEGNER JENS (DE)
International Classes:
B01J8/04; B01J8/42
Domestic Patent References:
| WO2009074373A1 | 2009-06-18 |
Foreign References:
| DE3415181A1 | 1985-10-31 | |||
| EP1106672A1 | 2001-06-13 |
Other References:
IAN R. BAXENDALE ET AL: "A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly", CHEMICAL COMMUNICATIONS, no. 24, 24 March 2006 (2006-03-24), pages 2566 - 2568, XP055000466, ISSN: 1359-7345, Retrieved from the Internet [retrieved on 20110610]
SASCHA CEYLAN ET AL: "Induktives Heizen in der organischen Synthese durch Verwendung funktionalisierter magnetischer Nanopartikel in Mikroreaktoren", ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH), NOT VERLAG CHEMIE :, vol. 120, no. 46, 3 November 2008 (2008-11-03), pages 9083 - 9086, XP009141533, ISSN: 0044-8249, [retrieved on 20081016], DOI: 10.1002/ANGE.200801474
JENS WEGNER ET AL: "Ten key issues in modern flow chemistry", CHEMICAL COMMUNICATIONS, vol. 47, no. 16, 15 March 2011 (2011-03-15), pages 4583 - 4592, XP055000468, ISSN: 1359-7345, Retrieved from the Internet [retrieved on 20110610]
SASCHA CEYLAN ET AL: "Induktives Heizen in der organischen Synthese durch Verwendung funktionalisierter magnetischer Nanopartikel in Mikroreaktoren", ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH), NOT VERLAG CHEMIE :, vol. 120, no. 46, 3 November 2008 (2008-11-03), pages 9083 - 9086, XP009141533, ISSN: 0044-8249, [retrieved on 20081016], DOI: 10.1002/ANGE.200801474
JENS WEGNER ET AL: "Ten key issues in modern flow chemistry", CHEMICAL COMMUNICATIONS, vol. 47, no. 16, 15 March 2011 (2011-03-15), pages 4583 - 4592, XP055000468, ISSN: 1359-7345, Retrieved from the Internet
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