METHOD OF COATING MEDICAL DEVICES

WIPO Patent Application WO2006014931

A3

Processes for coating implantable medical devices that improve the stability of therapeutic agents contained within the coating. In one embodiment, the process comprises: applying a primer coating on the implantable medical device; preparing a basecoat solution comprising polymers and a therapeutic agent and applying the basecoat solution to the implantable medical devices; preparing a topcoat solution comprising at least one polymer and applying the topcoat solution to the implantable medical devices coated with the basecoat solution; applying a solvent to partially redissolve the topcoat and basecoat while altering the surface finish and dissolution properties of the therapeutic agent; and final processing the implantable medical devices, including inspecting, packaging and sterilizing the coated medical devices.

AKERMAN EUGENA A (US)
CLEEREN DIRK (BE)
LLANOS GERARD (US)
MARYANOFF CYNTHIA A (US)
PAPANDREOU GEORGIOS (US)
RION WILLIAM L (US)
SIX KAREL (BE)
TODD THOMAS L (US)

PCT/US2005/026450

July 13, 2006

July 26, 2005

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CORDIS CORP (US)
AKERMAN EUGENA A (US)
CLEEREN DIRK (BE)
LLANOS GERARD (US)
MARYANOFF CYNTHIA A (US)
PAPANDREOU GEORGIOS (US)
RION WILLIAM L (US)
SIX KAREL (BE)
TODD THOMAS L (US)

A61F2/82; A61L27/34; A61L27/54; A61L31/10; A61L31/16

WO2003000308A1	2003-01-03
WO2003079936A1	2003-10-02

US6299604B1	2001-10-09
US20040063805A1	2004-04-01
US20030204245A1	2003-10-30
US20030083646A1	2003-05-01
US20020182392A1	2002-12-05

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