METHOD FOR COLLECTIVELY DETERMINING SENSITIVITY TO ANTI-CANCER THERAPEUTIC DRUG

WIPO Patent Application WO/2010/058974

A2

The present invention relates to a method for collectively testing sensitivity to both primary and secondary anti-cancer drugs through a one-time test under closely in vivo conditions. The present invention includes a method for collectively testing sensitivity of primary and secondary anti-cancer drugs to a tumor. The method comprises: (i) a step of preparing primary and secondary anti-cancer drug reaction plates; (ii) a step of injecting a tumor tissue specimen prepared from a patient to the reaction tablets of the primary and secondary anti-cancer drug reaction plates and culturing; (iii) a step of administering and reacting primary anti-cancer drug candidates to the reaction tablets of primary and secondary reaction plates; (iv) a step of measuring and analyzing sensitivity of the primary anti-cancer drug candidates treated to the reaction tablet of the primary anti-cancer drug reaction plate and administering and reacting secondary anti-cancer drug candidates to the tablet of the secondary anti-cancer drug reaction plate which have different combination with the primary anti-cancer drug; and (v) a step of measuring and analyzing sensitivity of secondary anti-cancer drug candidates treated to the reaction tablet of the secondary anti-cancer drug reaction plate.

WO/1996/004302	NOVEL TUMOR MARKER FOR LUNG CANCER
JP2007195533	METHOD FOR EVALUATING CELL, METHOD FOR EVALUATING CANCERIZATION OF MEASURED COMPONENT BY USING THE SAME, AND CANCER DIAGNOSIS KIT AND COMPUTER-READABLE MEDIUM
WO/2007/079250	DEVICES AND METHODS FOR ENRICHMENT AND ALTERATION OF CIRCULATING TUMOR CELLS AND OTHER PARTICLES

KIM JIN CHEON (KR)
KIM MOON BO (KR)

PCT/KR2009/006822

May 27, 2010

November 19, 2009

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ASAN FOUNDATION (KR)
KIM JIN CHEON (KR)
KIM MOON BO (KR)

G01N33/574; G01N33/48; G01N33/53

KR20060078078A

2006-07-05

YOON JOON PARK ET AL.: 'Chemosensitivity Test in Human Breast Cancer.' JOURNAL OF BREAST CANCER vol. 5, no. 1, pages 27 - 30
YONG SIK JUNG ET AL.: 'Can the Histoculture Drug Response Assay Predict the Clinical Results of Chemotherapy in Breast Cancer?' J. BREAST CANCER vol. 10, no. 3, 2007, pages 193 - 198
SINGH, B. ET AL.: 'Prediction of survival in patients with head and neck cancer using the histoculture drug response assay.' HEAD & NECK vol. 24, no. 5, 2002, pages 437 - 442

KIM, SOON WOONG (KR)
김순웅 (KR)

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