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Title:
METHOD AND COMPOSITION FOR TREATMENT AND/OR PREVENTION OF ANTIBIOTIC-RESISTANT MICROORGANISM INFECTIONS
Document Type and Number:
WIPO Patent Application WO2001045732
Kind Code:
A3
Abstract:
The present invention relates to a new composition, use and method to improve the cure of infections caused by antibiotic resistant microbial pathogens, in particular beta-lactam resistant microorganisms. Lactoferrin (LF) or Lactoferricin (LFC) can be administrated alone or in combination with antibiotic to affect growth, physiology and morphology of targeted microorganism. Lactoferrin increase susceptibility and can reverse resistance of microorganism to antibiotics.

Inventors:
DIARRA MOUSSA S (CA)
LACASSE PIERRE (CA)
PETITCLERC DENIS (CA)
Application Number:
PCT/CA2000/001517
Publication Date:
December 06, 2001
Filing Date:
December 19, 2000
Export Citation:
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Assignee:
MAJESTE LA REINE DU CHEF DU CA (CA)
DIARRA MOUSSA S (CA)
LACASSE PIERRE (CA)
PETITCLERC DENIS (CA)
International Classes:
A01N63/00; A61K31/43; A61K31/545; A61K31/7036; A61K31/7048; A61K38/16; A61K38/40; A61P31/00; A61P43/00; A61L2/16; (IPC1-7): A61K38/40; A61K38/01; A61L2/16; A01N63/02
Domestic Patent References:
WO1998040401A21998-09-17
Foreign References:
EP0629347A11994-12-21
US5198419A1993-03-30
Other References:
DATABASE WPI Section Ch Week 199517, Derwent World Patents Index; Class B04, AN 1995-126103, XP002171004
KUIPERS M E ET AL: "Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates.", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, (1999 NOV) 43 (11) 2635-41., XP001010102
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