Title:
METHOD FOR CONFIRMING PRDM14 EXPRESSION
Document Type and Number:
WIPO Patent Application WO/2019/065609
Kind Code:
A1
Abstract:
One embodiment of this invention is a method for confirming expression of the PRDM14 gene from blood or lymphatic fluid collected from a subject by: (1) detecting PRDM14 positive CTC which expresses the PRDM14 gene; or (2) measuring the concentration of at least one protein selected from the group consisting of leptin receptor (LEPR), macrophage-derived chemokine (MDC) and gamma-interferon (IFNγ).
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Inventors:
IMAI KOHZOH (JP)
ZEMBUTSU HITOSHI (JP)
TANIGUCHI HIROAKI (JP)
SAITOH ANRI (JP)
MIYAGI YOHEI (JP)
ZEMBUTSU HITOSHI (JP)
TANIGUCHI HIROAKI (JP)
SAITOH ANRI (JP)
MIYAGI YOHEI (JP)
Application Number:
PCT/JP2018/035395
Publication Date:
April 04, 2019
Filing Date:
September 25, 2018
Export Citation:
Assignee:
UNIV TOKYO (JP)
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)
International Classes:
G01N33/574; C07K14/47; C12N15/113; C12N15/13; C12Q1/02; C12Q1/6804
Foreign References:
| JP2013100286A | 2013-05-23 | |||
| JPS5219818B2 | 1977-05-31 |
Other References:
TANIGUCHI HIROAKI: "Development of the diagnosis methods using PRDM14 as a novel tu,or marker for intractable breast cancer and pancreatic cancer", 2014 OUTSOURCING PERFORMANCE REPORT, vol. 26, 1 March 2015 (2015-03-01), pages 13 - 16, XP009520544
NISHIKAWA N., CANCER RES., vol. 67, no. 20, 2007, pages 9649 - 9657
TANIGUCHI H. ET AL., ONCOTARGET, vol. 8, no. 29, 2017, pages 46856 - 46874
MORIYA C. ET AL., CARCINOGENESIS, vol. 38, no. 6, 2017, pages 638 - 648
SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 2001, COLD SPRING HARBOR LABORATORY PRESS
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", 1992, GREENE PUBLISHING ASSOCIATES
AUSUBEL ET AL.: "Short Protocols in Molecular Biology: A Compendium of Methods from Current Protocols in Molecular Biology", 1999, COLD SPRING HARBOR LABORATORY PRESS
HARLOWLANE: "Antibodies: A Laboratory Manual", 1990, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 3690444A4
NISHIKAWA N., CANCER RES., vol. 67, no. 20, 2007, pages 9649 - 9657
TANIGUCHI H. ET AL., ONCOTARGET, vol. 8, no. 29, 2017, pages 46856 - 46874
MORIYA C. ET AL., CARCINOGENESIS, vol. 38, no. 6, 2017, pages 638 - 648
SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 2001, COLD SPRING HARBOR LABORATORY PRESS
AUSUBEL ET AL.: "Current Protocols in Molecular Biology", 1992, GREENE PUBLISHING ASSOCIATES
AUSUBEL ET AL.: "Short Protocols in Molecular Biology: A Compendium of Methods from Current Protocols in Molecular Biology", 1999, COLD SPRING HARBOR LABORATORY PRESS
HARLOWLANE: "Antibodies: A Laboratory Manual", 1990, COLD SPRING HARBOR LABORATORY PRESS
See also references of EP 3690444A4
Attorney, Agent or Firm:
KUZUWA, Kiyoshi (JP)
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