Title:
METHOD OF CONTROLLING BIOTIC FUNCTION THROUGH MECHANICAL VIBRATION AND DEVICE THEREFOR
Document Type and Number:
WIPO Patent Application WO/2004/022726
Kind Code:
A1
Abstract:
A method of controlling biotic function, characterized by stimulating a biotic tissue or cell, bacterium or virus through mechanical vibration.
Inventors:
KISHIDA AKIO (JP)
FURUZONO TSUTOMU (JP)
MIYAZAKI KOZO (JP)
MASUZAWA TORU (JP)
FURUZONO TSUTOMU (JP)
MIYAZAKI KOZO (JP)
MASUZAWA TORU (JP)
Application Number:
PCT/JP2003/011306
Publication Date:
March 18, 2004
Filing Date:
September 04, 2003
Export Citation:
Assignee:
JP NAT CARDIOVASCULAR CT (JP)
KISHIDA AKIO (JP)
FURUZONO TSUTOMU (JP)
MIYAZAKI KOZO (JP)
MASUZAWA TORU (JP)
KISHIDA AKIO (JP)
FURUZONO TSUTOMU (JP)
MIYAZAKI KOZO (JP)
MASUZAWA TORU (JP)
International Classes:
C12N15/02; C12M1/00; C12M1/42; C12M3/00; C12N1/00; C12N1/21; C12N5/00; C12N5/07; C12N5/071; C12N7/00; C12N13/00; C12N15/87; (IPC1-7): C12N1/00; C12N15/00; C12N5/00; C12N1/21; C12N7/00; C12M1/00
Other References:
FROEHLICH J.E., ANASTASSIADES T.P.: "Possible limitation of growth in human fibroblast cultures by diffusion", J. CELL PHYSIOL., vol. 86, no. 3, SUPPL. 2, PT. 2, 1975, pages 67 - 80, XP002964752
CARVALHO R.S. ET AL.: "Predominant integrin ligands expressed by osteoblasts show preferential regulation in response to both cell adhesion and mechanical perturbation", J. CELL BIOCHEM., vol. 84, no. 3, 12 February 2002 (2002-02-12), pages 497 - 508, XP002964753
CEVC G. ET AL.: "Lipid vesicles and membrane fusion", ADVANCED DRUG DELIVERY REVIEWS, vol. 38, no. 3, 1999, pages 207 - 232, XP002964754
MORAWIETZ H. ET AL.: "Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells", CIRCULATION RES., vol. 84, no. 6, 1999, pages 678 - 687, XP002964755
SIGURDSON W.J. ET AL.: "Mechanical perturbation of cultured human endothelial cells causes rapid increases of intracellular calciun", AMERICAN JOURNAL OF PHYSIOLOGY, vol. 264, no. 6, PT. 2, 1993, pages H1745 - H1752, XP002964756
JOHNSON A.R. ET AL.: "Arachidonic acid metabolites and endothelial injury: studies with cultures of human endothelial cells", FEDERATION PROCEEDINGS, vol. 44, no. 1, PT 1, 1985, pages 19 - 24, XP002964757
CARVALHO R.S. ET AL.: "Predominant integrin ligands expressed by osteoblasts show preferential regulation in response to both cell adhesion and mechanical perturbation", J. CELL BIOCHEM., vol. 84, no. 3, 12 February 2002 (2002-02-12), pages 497 - 508, XP002964753
CEVC G. ET AL.: "Lipid vesicles and membrane fusion", ADVANCED DRUG DELIVERY REVIEWS, vol. 38, no. 3, 1999, pages 207 - 232, XP002964754
MORAWIETZ H. ET AL.: "Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells", CIRCULATION RES., vol. 84, no. 6, 1999, pages 678 - 687, XP002964755
SIGURDSON W.J. ET AL.: "Mechanical perturbation of cultured human endothelial cells causes rapid increases of intracellular calciun", AMERICAN JOURNAL OF PHYSIOLOGY, vol. 264, no. 6, PT. 2, 1993, pages H1745 - H1752, XP002964756
JOHNSON A.R. ET AL.: "Arachidonic acid metabolites and endothelial injury: studies with cultures of human endothelial cells", FEDERATION PROCEEDINGS, vol. 44, no. 1, PT 1, 1985, pages 19 - 24, XP002964757
Attorney, Agent or Firm:
Nishizawa, Toshio (Bldg. 7F 11-1, Minami-Aoyama 6-chom, Minato-ku Tokyo, JP)
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