Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR CULTURING 3-DIMENSIONAL LUNG CANCER ORGANOID AND METHOD FOR PREPARING PATIENT-DERIVED XENOGRAFT ANIMAL MODEL USING SAME
Document Type and Number:
WIPO Patent Application WO/2019/035618
Kind Code:
A1
Abstract:
The present invention relates to a method for culturing a 3-dimensional lung cancer organoid and a method for preparing a patient-derived xenograft animal model using the same. More specifically, the present invention relates to a method for culturing a 3-dimensional lung cancer organoid, a lung cancer organoid prepared by the method, a medium composition for culturing the lung cancer organoid, a method for preparing a xenograft animal model using the lung cancer organoid, a patient-derived lung cancer organoid xenograft animal model prepared by the method, and a method for analyzing the therapeutic efficacy of an anticancer agent and a method for screening an anticancer agent using the animal model.

Inventors:
JANG SE JIN (KR)
KIM MIN SUH (KR)
SUH YOUNG AH (KR)
MUN HYE MIN (KR)
OH JU HEE (KR)
Application Number:
PCT/KR2018/009254
Publication Date:
February 21, 2019
Filing Date:
August 13, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV ULSAN FOUND IND COOP (KR)
ASAN FOUND (KR)
International Classes:
C12N5/09; A01K67/027; G01N33/50
Domestic Patent References:
WO2016083613A22016-06-02
WO2016112172A12016-07-14
WO2016015158A12016-02-04
Foreign References:
KR20140133399A2014-11-19
KR101674468B12016-11-10
Other References:
"Current Protocols in Pharmacology", March 2013, JOHN WILEY & SONS, INC., Hoboken, NJ, USA, ISBN: 978-0-471-14175-4, article DEROSE, YOKO S.: "Patient-derived models of human breast cancer: Protocols for in vitro and in vivo applications in tumor biology and translational medicine", XP055576552, DOI: 10.1002/0471141755.ph1423s60
BARKAUSKAS, CHRISTINA E. ET AL.: "Lung organoids: current uses and future promise", DEVELOPMENT, vol. 144, no. 6, 15 March 2017 (2017-03-15), pages 986 - 997, XP055576557
See also references of EP 3670649A4
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
Download PDF: