Title:
METHOD FOR CULTURING MICROORGANISM AND METHOD FOR PRODUCING ORGANIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2017/169275
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a method for culturing a microorganism, whereby the microorganism can adapt to an inhibitor and thus fermentation inhibition can be sufficiently decreased, and a method for producing an organic compound wherein the microorganism obtained above or a processed product thereof is used. A method for culturing a microorganism in a liquid culture medium containing a saccharide, wherein, in the liquid culture medium, the carbonyl value based on compound(s) other than the saccharide is 100 μmol eq or greater per gram of the liquid culture medium. A method for producing an organic compound wherein the aforesaid microorganism or a processed product thereof is used.
Inventors:
SAWADA KAZUNORI (JP)
YUNOMURA SHUICHI (JP)
KAWAKAMI KIMINORI (JP)
YUNOMURA SHUICHI (JP)
KAWAKAMI KIMINORI (JP)
Application Number:
PCT/JP2017/006048
Publication Date:
October 05, 2017
Filing Date:
February 20, 2017
Export Citation:
Assignee:
MITSUBISHI CHEM CORP (JP)
International Classes:
C12N1/00; C12P7/02; C12P7/22; C12P7/40; C12P13/00
Other References:
YLITERVO PAIVI ET AL.: "Impact of Furfural on Rapid Ethanol Production Using a Membrane Bioreactor", ENER GIES, vol. 6, 2013, pages 1604 - 1617, XP055221624
ZHANG JIANGUO ET AL.: "Microbial Lipid Production from Corn Stover via Mortierella isabellina", APPL. BIOCHEM. BIOTECHNOL, vol. 174, 2014, pages 574 - 586, XP035378611
CHOI SUN YOUNG ET AL.: "Extreme furfural tolerance of a soil bacterium Enterobacter cloacae GGT036", J. BIOTECHNOL., vol. 193, 2015, pages 11 - 13, XP055425096
ALKASRAWI MALEK ET AL.: "Influence of strain and cultivation procedure on the performance of simultaneous saccharification and fermentation of steam pretreated spruce", ENZYME AND MICROBIAL TECHNOLOGY, vol. 38, no. 279-286, 2006, pages 284 - 285, XP027948705
MOHAGHEGHI ALI ET AL.: "Improving a recombinant Zymomonas mobilis strain 8b through continuous adaptation on dilute acid pretreated corn stover hydrolysate", BIOTECHNOLOGY FOR BIOFUELS, vol. 8, 2015, pages 55, XP021220644
HOU XIAORU ET AL.: "Improved inhibitor tolerance in xylose-fermenting yeast Spathaspora passalidarum by mutagenesis and protoplast fusion", APPL. MICROBIOL. BIOTECHNOL., vol. 93, 2012, pages 2591 - 2601, XP035024507
LI LIXIANG ET AL.: "Efficient production of 2,3-butanediol form corn stover hydrolysate by using a thermophilic Bacillus licheniformis strain", BIORESOURCE TECHNOLOGY, vol. 170, 2014, pages 256 - 261, XP055425099
ZHENG HUABAO ET AL.: "Increase in Furfural Tolerance in Ethanologenic Escherichia coli LY180 by plasmid-Based Expression of thyA", APPL. ENVIRON. MICROBIOL., vol. 78, no. 12, 2012, pages 4346 - 4352, XP055425101
PENG LILI ET AL.: "Bacillus sp. strain P38: An efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2- furfural", BIORESOURCE TECHNOLOGY, vol. 149, 2013, pages 169 - 176, XP028758724
KELLER FRED ET AL.: "Yeast Adaptation on Softwood Prehydrolysate", APPL. BIOCHEM. BIOTECHNOL., vol. 70-72, 1998, pages 137 - 148, XP002939010
CHUNG I. S. ET AL.: "Ethanol Fermentation of Crude Acid Hydrolyzate of Cellulose Using High- level Yeast Inocula", BIOTECHNOL. BIOENG., vol. 27, 1985, pages 308 - 315, XP002672754
QURESHI ABDUL SATTAR ET AL.: "Cellulosic Ethanol Fermentation Using Saccharomyces cerevisiae Seeds Cultured by Pretreated Corn Stover Materia", APPL. BIOCHEM. BIOTECHNOL., vol. 175, 2015, pages 3173 - 3183, XP035460896
UJOR VICTOR ET AL.: "Unorthodox methods for enhancing solvent production in solventogenic Clostridium species", APPL. MICROBIOL. BIOTECHNOL., vol. 100, 2015, pages 1089 - 1099, XP035870578
KANNA MACHI ET AL.: "Simultaneous Saccharification and Fermentation Using Environmental-adapted Yeast by Preculture", JOUNAL OF THE JAPAN INSTITUTE OF ENERGY, vol. 95, April 2016 (2016-04-01), pages 303 - 306, XP055425145
POL EDWIN VAN DER ET AL.: "Precultivation of Bacillus coagulans DSM2314 in the presence of furfural decreases inhibitory effects of lignocellulosic by-products during L(+)-lactic acid fermentation", APPL. MICROBIOL. BIOTECHNOL., vol. 100, July 2016 (2016-07-01), pages 10307 - 10319, XP036105290
RAN HONG ET AL.: "Analysis of biodegradation performance of furfural and 5-hydroxymethylfurfural by Amorphotheca resinae ZN1", BIOTECHNOLOGY FOR BIOFUELS, vol. 7, 2014, pages 51, XP021183687
ZHANG JIANGUO ET AL.: "Microbial Lipid Production from Corn Stover via Mortierella isabellina", APPL. BIOCHEM. BIOTECHNOL, vol. 174, 2014, pages 574 - 586, XP035378611
CHOI SUN YOUNG ET AL.: "Extreme furfural tolerance of a soil bacterium Enterobacter cloacae GGT036", J. BIOTECHNOL., vol. 193, 2015, pages 11 - 13, XP055425096
ALKASRAWI MALEK ET AL.: "Influence of strain and cultivation procedure on the performance of simultaneous saccharification and fermentation of steam pretreated spruce", ENZYME AND MICROBIAL TECHNOLOGY, vol. 38, no. 279-286, 2006, pages 284 - 285, XP027948705
MOHAGHEGHI ALI ET AL.: "Improving a recombinant Zymomonas mobilis strain 8b through continuous adaptation on dilute acid pretreated corn stover hydrolysate", BIOTECHNOLOGY FOR BIOFUELS, vol. 8, 2015, pages 55, XP021220644
HOU XIAORU ET AL.: "Improved inhibitor tolerance in xylose-fermenting yeast Spathaspora passalidarum by mutagenesis and protoplast fusion", APPL. MICROBIOL. BIOTECHNOL., vol. 93, 2012, pages 2591 - 2601, XP035024507
LI LIXIANG ET AL.: "Efficient production of 2,3-butanediol form corn stover hydrolysate by using a thermophilic Bacillus licheniformis strain", BIORESOURCE TECHNOLOGY, vol. 170, 2014, pages 256 - 261, XP055425099
ZHENG HUABAO ET AL.: "Increase in Furfural Tolerance in Ethanologenic Escherichia coli LY180 by plasmid-Based Expression of thyA", APPL. ENVIRON. MICROBIOL., vol. 78, no. 12, 2012, pages 4346 - 4352, XP055425101
PENG LILI ET AL.: "Bacillus sp. strain P38: An efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2- furfural", BIORESOURCE TECHNOLOGY, vol. 149, 2013, pages 169 - 176, XP028758724
KELLER FRED ET AL.: "Yeast Adaptation on Softwood Prehydrolysate", APPL. BIOCHEM. BIOTECHNOL., vol. 70-72, 1998, pages 137 - 148, XP002939010
CHUNG I. S. ET AL.: "Ethanol Fermentation of Crude Acid Hydrolyzate of Cellulose Using High- level Yeast Inocula", BIOTECHNOL. BIOENG., vol. 27, 1985, pages 308 - 315, XP002672754
QURESHI ABDUL SATTAR ET AL.: "Cellulosic Ethanol Fermentation Using Saccharomyces cerevisiae Seeds Cultured by Pretreated Corn Stover Materia", APPL. BIOCHEM. BIOTECHNOL., vol. 175, 2015, pages 3173 - 3183, XP035460896
UJOR VICTOR ET AL.: "Unorthodox methods for enhancing solvent production in solventogenic Clostridium species", APPL. MICROBIOL. BIOTECHNOL., vol. 100, 2015, pages 1089 - 1099, XP035870578
KANNA MACHI ET AL.: "Simultaneous Saccharification and Fermentation Using Environmental-adapted Yeast by Preculture", JOUNAL OF THE JAPAN INSTITUTE OF ENERGY, vol. 95, April 2016 (2016-04-01), pages 303 - 306, XP055425145
POL EDWIN VAN DER ET AL.: "Precultivation of Bacillus coagulans DSM2314 in the presence of furfural decreases inhibitory effects of lignocellulosic by-products during L(+)-lactic acid fermentation", APPL. MICROBIOL. BIOTECHNOL., vol. 100, July 2016 (2016-07-01), pages 10307 - 10319, XP036105290
RAN HONG ET AL.: "Analysis of biodegradation performance of furfural and 5-hydroxymethylfurfural by Amorphotheca resinae ZN1", BIOTECHNOLOGY FOR BIOFUELS, vol. 7, 2014, pages 51, XP021183687
Attorney, Agent or Firm:
KAWAGUCHI, Yoshiyuki et al. (JP)
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