Title:
METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS
Document Type and Number:
WIPO Patent Application WO2004080543
Kind Code:
A3
Abstract:
Methods and kits for decomposing organophosphorus compounds in non-aqueous media at ambient conditions are described. Insecticides, pesticides, and chemical warfare agents can be quickly decomposed to non-toxic products. The method comprises combining the organophosphorus compound with a non-aqueous solution, preferably an alcohol, comprising metal ions and at least a trace amount of alkoxide ions. In a first preferred embodiment, the metal ion is a lanthanum ion. In a second preferred embodiment, the metal ion is a transition metal.
Inventors:
BROWN R STANLEY (CA)
NEVEROV ALEXEI A (CA)
TSANG JOSEPHINE S W (CA)
NEVEROV ALEXEI A (CA)
TSANG JOSEPHINE S W (CA)
Application Number:
PCT/CA2004/000379
Publication Date:
November 18, 2004
Filing Date:
March 12, 2004
Export Citation:
Assignee:
UNIV KINGSTON (CA)
BROWN R STANLEY (CA)
NEVEROV ALEXEI A (CA)
TSANG JOSEPHINE S W (CA)
BROWN R STANLEY (CA)
NEVEROV ALEXEI A (CA)
TSANG JOSEPHINE S W (CA)
International Classes:
A62D3/30; A62D3/36; C07C29/12; A62D101/02; A62D101/04; A62D101/26; (IPC1-7): A62D3/00
Domestic Patent References:
| WO2002072206A1 | 2002-09-19 |
Foreign References:
| DD299458A7 | 1992-04-23 | |||
| US3079346A | 1963-02-26 |
Other References:
YANG Y-C: "CHEMICAL REACTIONS FOR NEUTRALISING CHEMICAL WARFARE AGENTS", CHEMISTRY AND INDUSTRY, CHEMICAL SOCIETY. LETCHWORTH, GB, 1 May 1995 (1995-05-01), pages 334 - 337, XP002909521, ISSN: 0009-3068
BROWN R S; NEVEROV A A, JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 2, vol. 2002, 26 March 2002 (2002-03-26), pages 1039 - 1049, XP002294627
YANG Y-C; BAKER J A; WARD J R: "Decontamination of Chemical Warfare Agents", CHEMICAL REVIEWS, vol. 92, no. 8, 1992, pages 1729 - 1743, XP002294626
TSANG J S; NEVEROV A A; BROWN R S: "Billion-fold Acceleration of the Methanolysis of Paraoxon Promoted by La(OTf)3 in Methanol", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 125, 28 May 2003 (2003-05-28), pages 7602 - 7607, XP002294628
YANG Y-C: "Chemical Detoxification of Nerve Agent VX", ACCOUNTS OF CHEMICAL RESEARCH, vol. 32, 1999, pages 109 - 115, XP002294629
BROWN R S; ZAMKANEI M: "Hydrolysis of Neutral Phosphate and Phosphonate Esters Catalysed by Co2+-chelates of Tris-imidazolyl Phosphines", INORGANICA CHIMICA ACTA, vol. 108, 1985, pages 201 - 207, XP002294630
NEVEROV A A; BROWN R S: "La3+-Catalyzed Methanolysis of Phosphphate Diesters. Remarkable Rate Acceleration of the Methanolysis of Diphenyl Phosphate, Methyl p-Nitrophenyl Phosphate, and Bis(p-nitrophenyl)Phosphate", INORGANIC CHEMISTRY, vol. 40, 2001, pages 3588 - 3595, XP002294639
BROWN R S; NEVEROV A A, JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 2, vol. 2002, 26 March 2002 (2002-03-26), pages 1039 - 1049, XP002294627
YANG Y-C; BAKER J A; WARD J R: "Decontamination of Chemical Warfare Agents", CHEMICAL REVIEWS, vol. 92, no. 8, 1992, pages 1729 - 1743, XP002294626
TSANG J S; NEVEROV A A; BROWN R S: "Billion-fold Acceleration of the Methanolysis of Paraoxon Promoted by La(OTf)3 in Methanol", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 125, 28 May 2003 (2003-05-28), pages 7602 - 7607, XP002294628
YANG Y-C: "Chemical Detoxification of Nerve Agent VX", ACCOUNTS OF CHEMICAL RESEARCH, vol. 32, 1999, pages 109 - 115, XP002294629
BROWN R S; ZAMKANEI M: "Hydrolysis of Neutral Phosphate and Phosphonate Esters Catalysed by Co2+-chelates of Tris-imidazolyl Phosphines", INORGANICA CHIMICA ACTA, vol. 108, 1985, pages 201 - 207, XP002294630
NEVEROV A A; BROWN R S: "La3+-Catalyzed Methanolysis of Phosphphate Diesters. Remarkable Rate Acceleration of the Methanolysis of Diphenyl Phosphate, Methyl p-Nitrophenyl Phosphate, and Bis(p-nitrophenyl)Phosphate", INORGANIC CHEMISTRY, vol. 40, 2001, pages 3588 - 3595, XP002294639
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