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Title:
METHOD FOR DETECTING DILUTE PARTICLES IN SOLUTION USING LUMINESCENT PROBE
Document Type and Number:
WIPO Patent Application WO/2012/014778
Kind Code:
A1
Abstract:
Disclosed is an optical analysis technique that can detect the status or properties of target particles in a sample solution that has a low concentration or number density of said target particles, using an optical probe. Said optical analysis technique uses an optical system that can detect light from a microscopic region of a solution, such as a confocal microscope or a multiphoton microscope optical system, to detect light from the optical probe that has bound to the target particles, while changing the position of the microscopic region in the sample solution (i.e., while scanning the sample solution by microscopic regions), and, as a result, individually detect particles that traverse the microscopic regions, making it possible to count the particles and obtain information on the concentration or number density thereof.

Inventors:
TANABE, Tetsuya (43-2 Hatagaya 2-chom, Shibuya-ku Tokyo 72, 〒1510072, JP)
田邊 哲也 (〒72 東京都渋谷区幡ヶ谷2丁目43番2号オリンパス株式会社内 Tokyo, 〒1510072, JP)
NAKATA, Hidetaka (43-2 Hatagaya 2-chom, Shibuya-ku Tokyo 72, 〒1510072, JP)
中田 秀孝 (〒72 東京都渋谷区幡ヶ谷2丁目43番2号オリンパス株式会社内 Tokyo, 〒1510072, JP)
HANASHI, Takuya (43-2 Hatagaya 2-chom, Shibuya-ku Tokyo 72, 〒1510072, JP)
Application Number:
JP2011/066576
Publication Date:
February 02, 2012
Filing Date:
July 21, 2011
Export Citation:
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Assignee:
OLYMPUS CORPORATION (43-2, Hatagaya 2-chome Shibuya-ku Tokyo, 72, 〒1510072, JP)
オリンパス株式会社 (〒72 東京都渋谷区幡ヶ谷2丁目43番2号 Tokyo, 〒1510072, JP)
TANABE, Tetsuya (43-2 Hatagaya 2-chom, Shibuya-ku Tokyo 72, 〒1510072, JP)
田邊 哲也 (〒72 東京都渋谷区幡ヶ谷2丁目43番2号オリンパス株式会社内 Tokyo, 〒1510072, JP)
NAKATA, Hidetaka (43-2 Hatagaya 2-chom, Shibuya-ku Tokyo 72, 〒1510072, JP)
中田 秀孝 (〒72 東京都渋谷区幡ヶ谷2丁目43番2号オリンパス株式会社内 Tokyo, 〒1510072, JP)
International Classes:
G01N21/64; G01N15/14; G01N33/542
Attorney, Agent or Firm:
AKASHI, Masaki et al. (5F YH Bldg, 6-8 Shinkawa 2-chome, Chuo-k, Tokyo 33, 〒1040033, JP)
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Claims: