Title:
METHOD FOR DETECTING INFANTILE ACCUMULATION-ELIMINATING GRANULES
Document Type and Number:
WIPO Patent Application WO/2020/140670
Kind Code:
A1
Abstract:
Disclosed is a quality control method for infantile accumulation-eliminating granules. The method comprises: using thin-layer chromatography to perform qualitative identification on parched Crataegi fructus and Pharbitidis semen in infantile accumulation-eliminating granules; using high-performance liquid chromatography to determine the content of an activation component, arecoline, in the infantile accumulation-eliminating granules to carry out quantitative control; and using a potentiometric titration method to determine the content of organic acids in the infantile accumulation-eliminating granules. The method of the present invention is simple, has a good degree of separation, strong specificity and good reproducibility, thereby effectively guaranteeing the quality and curative effect of the infantile accumulation-eliminating granules, and having very strong practicality.
More Like This:
| WO/1997/001752 | METHOD FOR QUANTIFYING SPHINGOSINE AND FOR DIAGNOSING PLATELET ACTIVATION |
| WO/1990/004596 | ISOLATION OF OLIGOSACCHARIDES |
Inventors:
LIU JINGPING (CN)
LIU QUANGUO (CN)
CHEN KELING (CN)
LIN GUO (CN)
LIU QUANGUO (CN)
CHEN KELING (CN)
LIN GUO (CN)
Application Number:
PCT/CN2019/122864
Publication Date:
July 09, 2020
Filing Date:
December 04, 2019
Export Citation:
Assignee:
HAINAN HULUWA PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
G01N30/90; G01N30/02; G01N30/06; G01N30/74; G01N30/94; G01N30/95; G01N31/16
Foreign References:
| CN109596768A | 2019-04-09 | |||
| CN105548454A | 2016-05-04 |
Other References:
LIU CHUNFENG ; YU BAIQING: "Identification of Huaji San by TLC", HERALD OF MEDICINE, vol. 29, no. 5, 1 May 2010 (2010-05-01), pages 657 - 658, XP009521855, ISSN: 1004-0781, DOI: 20200113105048Y
HUANG YUN, OUYANG LIMING, HUANG SHICHAO: "Study on the Characteristics of Betel Nut on C18 Column", CHINA PHARMACIST, vol. 15, no. 2, 5 February 2012 (2012-02-05), pages 202 - 204, XP009521856, ISSN: 1008-049X
CHEN ZHAN GUO, LU JIU RU: "Determination for free total content of organic acid by direct potential titration in compound Chinese herbal medicine containing Fructus mume", JOURNAL OF SHAANXI NORMAL UNIVERSITY (NATURAL SCIENCE EDITION), vol. 28, no. 4, 5 December 2000 (2000-12-05), pages 78 - 80, XP009521857, DOI: 10.15983/j.cnki.jsnu.2000.04.021
ZHAO YANYI : "Betelnut", PHARMACOPOEIA OF THE PEOPLE'S REPUBLIC OF CHINA 2015, vol. 1, 30 June 2015 (2015-06-30), pages 365, XP009521859, ISBN: 978-7-5067-7337-9
HUANG YUN, OUYANG LIMING, HUANG SHICHAO: "Study on the Characteristics of Betel Nut on C18 Column", CHINA PHARMACIST, vol. 15, no. 2, 5 February 2012 (2012-02-05), pages 202 - 204, XP009521856, ISSN: 1008-049X
CHEN ZHAN GUO, LU JIU RU: "Determination for free total content of organic acid by direct potential titration in compound Chinese herbal medicine containing Fructus mume", JOURNAL OF SHAANXI NORMAL UNIVERSITY (NATURAL SCIENCE EDITION), vol. 28, no. 4, 5 December 2000 (2000-12-05), pages 78 - 80, XP009521857, DOI: 10.15983/j.cnki.jsnu.2000.04.021
ZHAO YANYI : "Betelnut", PHARMACOPOEIA OF THE PEOPLE'S REPUBLIC OF CHINA 2015, vol. 1, 30 June 2015 (2015-06-30), pages 365, XP009521859, ISBN: 978-7-5067-7337-9
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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