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Title:
METHOD FOR DETECTING KIDNEY DISEASES AND PATHOLOGICAL CONTROL
Document Type and Number:
WIPO Patent Application WO/2000/014543
Kind Code:
A1
Abstract:
A method for detecting kidney diseases at the early stage characterized by measuring the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample collected from a subject and comparing the thus measured concentration with the human lipocalin-type prostaglandin D synthase concentration of body fluid samples obtained from healthy subjects; and a method for pathologically controlling kidney diseases characterized by measuring the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample collected from a subject and evaluating the glomerular filtration level of the patient therefrom.

Inventors:
ODA HIROSHI (JP)
SEIKI KOSUKE (JP)
NAKAJIMA HIROSHI (JP)
SATO NOBUYUKI (JP)
URADE YOSHIHIRO (JP)
HIRAWA NOBUHITO (JP)
UEHARA YOSHIO (JP)
Application Number:
PCT/JP1999/004804
Publication Date:
March 16, 2000
Filing Date:
September 03, 1999
Export Citation:
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Assignee:
MARUHA CORP (JP)
OSAKA BIOSCIENCE INST (JP)
JAPAN SCIENCE & TECH CORP (JP)
ODA HIROSHI (JP)
SEIKI KOSUKE (JP)
NAKAJIMA HIROSHI (JP)
SATO NOBUYUKI (JP)
URADE YOSHIHIRO (JP)
HIRAWA NOBUHITO (JP)
UEHARA YOSHIO (JP)
International Classes:
G01N33/50; C12Q1/533; G01N33/573; G01N33/68; G01N33/70; G01N33/88; (IPC1-7): G01N33/573
Domestic Patent References:
WO1997016461A11997-05-09
WO1997016461A11997-05-09
Other References:
HOFFMAN A ET AL: "Molecular Characterization of beta-Trace Protein in Human Serum and Urine: a Potential Diagnostic Marker for Renal Diseases", GLYCOBIOLOGY, vol. 7, no. 4, 1997, pages 499 - 506, XP002922094
AKIRA SEKIKAWA ET AL., THE 41ST ANNUAL MEETING OF JAPAN DIABETES SOCIETY
See also references of EP 1111387A4
Attorney, Agent or Firm:
Hiraki, Yusuke (3rd Floor 17-, To ranomon 1-chome Minato-ku Tokyo, JP)
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