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Title:
METHOD FOR DETECTING METHYLATION OF SYNDECAN 2 (SDC2) GENE
Document Type and Number:
WIPO Patent Application WO/2018/194280
Kind Code:
A1
Abstract:
The present invention relates to: a method for detecting the methylation of a CpG island region of a Syndecan 2 (SDC2) gene; a composition for detecting the methylation of a CpG island region of an SDC2 gene; and a kit for detecting the methylation of a CpG island region of an SDC2 gene and, more specifically, to: a method for detecting the methylation of a CpG island region of an SDC2 gene by amplifying methylated SDC2 DNA by using a forward primer and/or a reverse primer, which complementarily binds to methylated SDC2 DNA and comprises at least one CG and/or GC; a composition for detecting the methylation of a CpG island region of an SDC2 gene, containing the primer; and a kit for detecting the methylation of a CpG island region of an SDC2 gene, containing the primer.

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Inventors:
AN SUNGWHAN (KR)
OH TAEJEONG (KR)
Application Number:
PCT/KR2018/003415
Publication Date:
October 25, 2018
Filing Date:
March 23, 2018
Export Citation:
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Assignee:
GENOMICTREE INC (KR)
International Classes:
C12Q1/6886
Foreign References:
KR20150114844A2015-10-13
KR20110084487A2011-07-25
KR20140059125A2014-05-15
KR20160041905A2016-04-18
Other References:
"Hints for Optimizing Bisulfite Primer Design", EPIGENIE WEBSITE, 12 September 2014 (2014-09-12), XP055560236, Retrieved from the Internet
THOMASSIN, H. ET AL.: "MethylQuant: a Sensitive Method for Quantifying Methylation of Specific Cytosines within the Genome", NUCLEIC ACIDS RESEARCH, vol. 32, no. 21, 2 December 2004 (2004-12-02), pages 1 - 9, XP055560238
LU , J. ET AL.: "PrimerSuite: a High-throughput Web-based Primer Design Program for Multiplex Bisulfite PCR", SCIENTIFIC REPORTS, vol. 7, no. 1, 24 January 2017 (2017-01-24), pages 1 - 12, XP055560239
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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