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Title:
METHOD FOR DETECTING PROGNOSIS OF CANCER
Document Type and Number:
WIPO Patent Application WO2004093662
Kind Code:
A3
Abstract:
It is to provide a method and a kit for detecting the prognosis of cancer at high accuracy in a simple and rapid manner at low cost. The method is specifically a method for detecting the prognosis of cancer, at least including a step of detecting core-2 beta 1,6-acetylglucosaminyltransferase in a sample collected from a biological organism to examine the relationship between the results of the detection and the prognosis of cancer in the biological organism, wherein core-2 beta1,6-acetylglucosaminyltransferase is preferably core-2 beta1,6-acetylglucosaminyltransferase-I; the biological organism is preferably human body; and the sample is preferably a living tissue.

Inventors:
OHYAMA CHIKARA (JP)
FUKUDA MINORU (US)
Application Number:
PCT/US2004/006085
Publication Date:
November 25, 2004
Filing Date:
March 19, 2004
Export Citation:
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Assignee:
SEIKAGAKU KOGYO CO LTD (JP)
BURNHAM INST (US)
OHYAMA CHIKARA (JP)
FUKUDA MINORU (US)
International Classes:
A61K38/00; C07K2/00; C07K4/00; C07K5/00; C07K7/00; C07K14/00; C07K16/00; C07K17/00; C12Q1/00; C12Q1/48; G01N33/53; G01N33/567; G01N33/574; A61B; (IPC1-7): C12Q1/00; G01N33/53; G01N33/567; G01N33/574; A61K38/00; C07K2/00; C07K4/00; C07K5/00; C07K7/00; C07K14/00; C07K16/00; C07K17/00
Other References:
SHIMODAIRA K. ET AL: "Carcinoma-associated expression of core 2 beta-1,6-N-acetylglucosaminyltransferase gene in human colorectal cancer: Role of O-glycans in tumor progression", CANCER RESEARCH, vol. 57, 1 December 1997 (1997-12-01), pages 5201 - 5206, XP002146297
SCHNEIDER F. ET AL: "Overexpression of sialyltransferase CMP-sialic acid:Gal beta 1,3GalNAc-R alpha 6-Sialyltransferase is related to poor patient survival in human colorectal carcinomas", CANCER RESEARCH, vol. 61, 1 June 2001 (2001-06-01), pages 4605 - 4611, XP002232470
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