METHOD FOR DETECTION OF INFECTION WITH HUMAN CYTOMEGALOVIRUS

WIPO Patent Application WO/2012/005238

A1

Disclosed is a novel and highly practically available means for detecting the infection with an HCMV with high sensitivity. A full-length protein of each of 15 kinds of HCMV proteins is synthesized, and the reactivity of the full-length protein with serum collected from each of HCMV infection patients is extensively examined. As a result, it is found that all of infection patients can be detected completely when a full-length pp28 protein is used as an antigen. The full-length pp28 protein can be synthesized in a large amount in the form of a recombinant protein and purified using Escherichia coli, and can be used for commercial purposes as an antigen for use in the test on HCMVs.

FUJII, Nobuyuki (62-5 Nihonbashi-Hamacho 2-chome, Chuo-k, Tokyo 07, 〒1030007, JP)
藤井　信之 (〒07 東京都中央区日本橋浜町二丁目６２番５号　富士レビオ株式会社内 Tokyo, 〒1030007, JP)
HONDA, Hideo (62-5 Nihonbashi-Hamacho 2-chome, Chuo-k, Tokyo 07, 〒1030007, JP)

JP2011/065343

January 12, 2012

July 05, 2011

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FUJIREBIO INC. (62-5, Nihonbashi-Hamacho 2-chome Chuo-k, Tokyo 07, 〒1030007, JP)
富士レビオ株式会社 (〒07 東京都中央区日本橋浜町二丁目６２番５号 Tokyo, 〒1030007, JP)
FUJII, Nobuyuki (62-5 Nihonbashi-Hamacho 2-chome, Chuo-k, Tokyo 07, 〒1030007, JP)
藤井　信之 (〒07 東京都中央区日本橋浜町二丁目６２番５号　富士レビオ株式会社内 Tokyo, 〒1030007, JP)
HONDA, Hideo (62-5 Nihonbashi-Hamacho 2-chome, Chuo-k, Tokyo 07, 〒1030007, JP)

G01N33/569; C07K14/045; G01N33/53

TANIGAWA, Hidejiro (Patent Firm 6F, SK Iidabashi Bldg., 5-12, Iidabashi 4-chome, Chiyoda-k, Tokyo 72, 〒1020072, JP)

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