METHOD FOR DETERMINATION OF ANTIGEN AND ANTIBODY AGAINST THE ANTIGEN, AND DETERMINATION REAGENT FOR USE IN THE METHOD

WIPO Patent Application WO/2008/029873

A1

For determining an antigen or an antibody against the antigen in a sample, a determination reagent is used which comprises an antibody capable of causing an antigen-antibody reaction with the antigen contained in the sample and an antigen capable of causing an antigen-antibody reaction with both of the antibody contained in the sample and the antibody contained in the reagent. Either one of the antigen and the antibody in the reagent is supported on a microparticle. The sample is mixed with the reagent. The antigen or the antibody in the sample can be determined based on the degree of increase or decrease in coagulation caused by the antigen-antibody reaction. It becomes possible to determine both of an antigen and an antibody against the antigen in a sample accurately using a single reagent.

KOJIMA RYO (JP)
INOUE SATOSHI (JP)
ARAI SATOSHI (JP)
KATAYAMA KATSUHIRO (JP)
NODA KENTA (JP)

PCT/JP2007/067385

March 13, 2008

September 06, 2007

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NITTO BOSEKI CO LTD (JP)
KOJIMA RYO (JP)
INOUE SATOSHI (JP)
ARAI SATOSHI (JP)
KATAYAMA KATSUHIRO (JP)
NODA KENTA (JP)

G01N33/53; G01N33/543

JP2005172546A	2005-06-30
JP2001504572A	2001-04-03
JPH0448265A	1992-02-18
JPH032565A	1991-01-08

NOBUHIKO KUBO ET AL., NIHON RINSHOU, vol. 57, 1999, pages 10 - 12
TAKAKO MIGITA ET AL., NIHON YUKETSU GAKKAI-ZASSHI, vol. 50, no. 3, 2004, pages 419 - 424

ASAMURA, Kiyoshi et al. (New Ohtemachi Bldg. 2-1, Ohtemachi 2-chome, Chiyoda-k, Tokyo 04, JP)

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