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Title:
METHOD FOR DETERMINING STAGE OF PERIODONTAL DISEASE
Document Type and Number:
WIPO Patent Application WO/2017/175673
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a method for objectively and highly accurately evaluating a stage of periodontal disease on the basis of a result of measuring an examination object obtained from an oral cavity. A method for evaluating a stage of periodontal disease by using as an index an amount of occult blood, and a number of white blood cells or total protein concentration, in an examination object obtained from an oral cavity, wherein the method includes: a step for determining whether the amount of occult blood is positive or negative; and a step for determining, when the amount of occult blood is positive, whether the number of white blood cells is positive or negative, or a step for determining, when the amount of occult blood is negative, whether the total concentration of proteins is positive or negative. The method preferably further includes a step for using ammonia concentration as an index and determining whether the ammonia concentration is positive or negative.

Inventors:
MAKI RIICHI (JP)
FUJIKAWA HARUHIKO (JP)
FUKUTA ISAO (JP)
Application Number:
PCT/JP2017/013551
Publication Date:
October 12, 2017
Filing Date:
March 31, 2017
Export Citation:
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Assignee:
LION CORP (JP)
ARKRAY INC (JP)
International Classes:
G01N33/50; G01N33/49; G01N33/68
Domestic Patent References:
WO1995012124A11995-05-04
WO2012090995A12012-07-05
Foreign References:
JP2002253584A2002-09-10
JP2013184971A2013-09-19
JP2016001129A2016-01-07
JPH074273B21995-01-25
JP2010256190A2010-11-11
JP2005201768A2005-07-28
JP2015529333A2015-10-05
JP2008520366A2008-06-19
US20160055296A12016-02-25
Other References:
CHIYOKO UCHIYAMA: "Daeki ni yoru Sogoteki na Koku Kensaho no Kaihatsu (Dai 3 Ho) Takomoku Daeki Kensa System (AL-55) no Shishubyo Kensa Komoku no Monitoring Yuyosei ni Tsuite", NIHON-SHISHŪBYŌ-GAKKAI-KAISHI [JOURNAL OF THE JAPANESE SOCIETY OF PERIODONTOLOGY], vol. 57, 12 September 2014 (2014-09-12), pages 123, XP009515885, ISSN: 0385-0110
EIJI NISHINAGA: "Daeki ni yoru Sogoteki na Koku Kensaho no Kaihatsu (Dai 2 Ho) Takomoku Daeki Kensa System (AL-55) no Kokunai Shojo no Suii ni Taisuru Monitoring Yuyosei ni Tsuite", NIPPON SHIKA NINGEN DOCK GAKKAI SOKAI-GAKUJUTSU TAIKAI [THE 16TH ACADEMIC CONFERENCE OF JAPAN DENTAL NURSING DOCK SOCIETY]; 13-14/12/2013, vol. 16 th, 2013, pages 19, XP009515886
EIJI NISHINAGA: "Development of Comprehensive Salivary Test System: -Efficiency of a Newly- developed Salivary Multi-test System (AL-55)", NIHON SHIKA HOZONGAKU ZASSHI, vol. 58, no. 3, 30 June 2015 (2015-06-30), pages 219 - 228, XP055528106
RIICHI MAKI: "Daeki ni yoru Sogoteki na Koku Kensaho no Kaihatsu (Dai 2 Ho) Takomoku Daeki Kensa System (AL-55) no Shishubyo Kensa Komoku no Yuyosei ni Tsuite", PROGRAM AND ABSTRACTS OF ANNUAL MEETING OF THE JAPANESE SOCIETY OF PERIODONTOLOGY, vol. 56, 8 April 2013 (2013-04-08), pages 107, XP009515884, ISSN: 0385-0110
DAVIS, IAN J: "A cross-sectional survey of bacterial species in plaque from client owned dogs with healthy gingiva, gingivitis or mild periodontitis", PLOS ONE, vol. 8, no. 12, 2013, pages e83158, XP055431181
RAESTE, A M: "Rate of migration of oral leukocytes in patients with periodontitis", SCAND J DENT RES, vol. 86, no. 1, January 1978 (1978-01-01), pages 43 - 51, XP055431184
TOHICHI MAKI: "O-27 Takomoku Daeki Kensa System (AL- 55) no Shishubyo Screening Kensa toshite no Jitsuyosei Kento = [Periodontal disease screen of multi-item saliva examination system (AL-55) Examination as practicality inspection]", JOURNAL OF THE JAPANESE SOCIETY OF PERIODONTOLOGY, vol. 58, no. Suppl. 1, 18 April 2016 (2016-04-18), pages 122 - 122, XP009514050, ISSN: 0385-0110
Attorney, Agent or Firm:
SANUKI, Shinichi et al. (JP)
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